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merck millipore,默克密理博,MABC774,Anti-phospho-NDRG1 (Ser330), clone EPR5594, Rabbit Monoclonal Antibody
产品名称:Anti-phospho-NDRG1 (Ser330), clone EPR5594, Rabbit Monoclonal Antibody
产品型号:MABC774
This Anti-phospho-NDRG1 (Ser330), clone EPR5594, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of phospho-NDRG1 (Ser330).
merck millipore,默克密理博,MABC774,Anti-phospho-NDRG1 (Ser330), clone EPR5594, Rabbit Monoclonal Antibody
- 产品介绍
- merck millipore,默克密理博,MABC774,Anti-phospho-NDRG1 (Ser330), clone EPR5594, Rabbit Monoclonal Antibody
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Unpurified Monoclonal Antibody 描述 产品目录编号 MABC774 描述 Anti-phospho-NDRG1 (Ser330), clone EPR5594, Rabbit Monoclonal Antibody Alternate Names - Rit42
- Protein NDRG1
- Differentiation-related gene 1 protein
- DRG-1
- N-myc downstream-regulated gene 1 protein
- Nickel-specific induction protein Cap43
- Reducing agents and tunicamycin-responsive protein
- RTP
背景信息 Protein NDRG1, also known as Differentiation-related gene 1 protein (DRG-1) or N-myc downstream-regulated gene 1 protein or Nickel-specific induction protein Cap43 or Reducing agents and tunicamycin-responsive protein (RTP) or Rit42, and encoded by the gene name NDRG1 or CAP43 or DRG1 or RTP, is a member of the NDRG family, which is a part of the alpha/beta hydrolase superfamily. It is mostly found in the cytoplasm, but at times migrates to the cell membrane and adherens junctions. NDRG1 is up-regulated during hypoxia and this may infer a role in protection from ischemic cell damage. NDRG1 levels in certain cancers may be a useful diagnostic tool. NDRG1 is also required for p53-mediated caspase activation and apoptosis. NDRG1 overexpression may be a great indicator of tumor aggressiveness and prognosis. Mutations in NDRG1 have been assoicated with Charcot-Marie-Tooth disease 4D. 产品信息 格式 Unpurified 演示 Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol. 应用 应用 This Anti-phospho-NDRG1 (Ser330), clone EPR5594, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of phospho-NDRG1 (Ser330). 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:100-250 dilution from a representative lot detected phospho-NDRG1 (Ser330) in human kidney tissue.
Produced in collaboration with Epitomics™生物信息 免疫原品种 Synthetic peptide corresponding to human phospho-NDRG1 (Ser330). 克隆 EPR5594 浓缩 Please refer to lot specific datasheet. 宿主 Rabbit 同种型 IgG 品种反应性 Human Species Reactivity Note Human 抗体类型 Monoclonal Antibody 基因符号 - RTP
- NDRG1
- CAP43
- DRG1
纯化方法 Unpurified UniProt编号 - Q92597
产品使用声明 质量保证 Evaluated by Western Blotting in untreated HEK293 and Calyculin A treated HEK293 cell lysates.
Western Blotting Analysis: A 1:10,000-50,000 dilution of this antibody detected phospho-NDRG1 (Ser330) in untreated HEK293 and Calyculin A treated HEK293 cell lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 100 µL
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