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merck millipore,默克密理博,MABC740,Anti-DAPK1, clone EPR1818(2), Rabbit Monoclonal Antibody
产品名称:Anti-DAPK1, clone EPR1818(2), Rabbit Monoclonal Antibody
产品型号:MABC740
This Anti-DAPK1, clone EPR1818(2), Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry and Immunofluorescence for the detection of DAPK1.
merck millipore,默克密理博,MABC740,Anti-DAPK1, clone EPR1818(2), Rabbit Monoclonal Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Unpurified Monoclonal Antibody 描述 产品目录编号 MABC740 描述 Anti-DAPK1, clone EPR1818(2), Rabbit Monoclonal Antibody Alternate Names - DAP kinase 1
- Death-associated protein kinase 1
背景信息 Death Associated Protein Kinase (DAP kinase) is a Ca2+/calmodulin-dependent, cytoskeletal associated protein kinase whose expression is implicated in the sensitivity of cells to apoptotic effects of TNF-a and interferon-g. Deletion of the calmodulin-binding domain resulted in a constitutively active mutant with a more potent cytotoxic effect. In contrast, the catalytically inactive mutant exerted a dominant negative effect, reducing cytotoxicity and protecting cells from interferon-γ induced cell death. DAP Kinase expression is frequently lost in human carcinomas and B-cell leukemia, and lower levels of expression correlates with high rates of metastasis. 产品信息 格式 Unpurified 演示 Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol. 应用 应用 This Anti-DAPK1, clone EPR1818(2), Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry and Immunofluorescence for the detection of DAPK1. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:250-500 dilution from a representative lot detected DAPK1 in human breast tissue.
Immunofluorescence Analysis: A 1:100-250 dilution from a representative lot detected DAPK1 in HeLa cells.
Produced in collaboration with Epitomics™生物信息 免疫原品种 Synthetic peptide corresponding to human DAPK1. 克隆 EPR1818(2) 浓缩 Please refer to lot specific datasheet. 宿主 Rabbit 同种型 IgG 品种反应性 Human Species Reactivity Note Human 抗体类型 Monoclonal Antibody 基因符号 - DAPK
- DAPK1
纯化方法 Unpurified UniProt编号 - P53355
产品使用声明 质量保证 Evaluated by Western Blotting in HEK293, HeLa, HepG2, Raji and A549 cell lysates .
Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected DAPK1 in HEK293, HeLa, HepG2, Raji and A549 cell lysates .使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 100 µL
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