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merck millipore,默克密理博,MABC682,Anti-MATK Antibody, clone 9D7
产品名称:Anti-MATK Antibody, clone 9D7
产品型号:MABC682
Detect Megakaryocyte-associated tyrosine-protein kinase using this mouse monoclonal antibody, Anti-MATK Antibody, clone 9D7 validated for use in western blotting & Flow Cytometry.
merck millipore,默克密理博,MABC682,Anti-MATK Antibody, clone 9D7
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC, WB M Ascites Monoclonal Antibody 描述 产品目录编号 MABC682 描述 Anti-MATK Antibody, clone 9D7 Alternate Names - Tyrosine-protein kinase CTK
- Megakaryocyte-associated tyrosine-protein kinase
- CSK homologous kinase
- CHK
- Hematopoietic consensus tyrosine-lacking kinase
- Protein kinase HYL
背景信息 Megakaryocyte-associated tyrosine-protein kinase (MATK), or alternatively CSK homologous kinase (CHK), Hematopoietic consensus tyrosine-lacking kinase, Protein kinase HYL, Tyrosine-protein kinase CTK, is an important kinase in hematopoietic signal transduction in blood cells as well as in other cells such as neurons and T cells. As its name would imply, MATK was first associated with megakaryocytes, the cells that give rise to platelets. MATK is able to phosphorylate and inactivate Src family kinases and may play a role in the regulation of proliferation of some cells such as T cells. In the nervous system MATK (called CHK in the older literature) plays a distinct role in the development of the CNS. MATK was found to be expressed in a developmental manner and expressed not only in developing neurons but also astrocytes and oligodendrocytes, but not in any of the associated tumors from these cell types, possibly indicating that it is the loss of expression of MATK activity that impacts tumorigenesis. EMD-Millipore’s Anti-MATK monoclonal antibody has been tested in western blot using K562 cell lysates and in flow cytometry using permeabilized K562 cells in culture. 产品信息 格式 Ascites 控制 - K562 cell lysate
演示 Purified mouse monoclonal liquid in PBS containing up to 0.1% sodium azide and 50% glycerol. 应用 应用 Detect Megakaryocyte-associated tyrosine-protein kinase using this mouse monoclonal antibody, Anti-MATK Antibody, clone 9D7 validated for use in western blotting & Flow Cytometry. 主要应用 - Flow Cytometry
- Western Blotting
应用说明 Flow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected MATK in K562 cells.
Optimal working dilutions must be determined by end user.
生物信息 免疫原品种 Purified recombinant fragment of human MATK expressed in E. Coli. 克隆 9D7 宿主 Mouse 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody 基因符号 - HYL
- MATK
- CTK
纯化方法 Antigen Affinity purified UniProt编号 - P42679
产品使用声明 质量保证 Evaluated by Western Blotting in K562 cell lysate.
Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected MATK in K562 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 100 µL
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