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merck millipore,默克密理博,MABC681,Anti-ETV4 Antibody, clone 1A2G3
产品名称：Anti-ETV4 Antibody, clone 1A2G3
产品型号：MABC681
Detect ETS translocation variant 4 protein using this mouse monoclonal antibody, Anti-ETV4 Antibody & clone 1A2G3 validated for use in western blotting.
merck millipore,默克密理博,MABC681,Anti-ETV4 Antibody, clone 1A2G3
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB M Ascites Monoclonal Antibody 描述 产品目录编号 MABC681 描述 Anti-ETV4 Antibody, clone 1A2G3 Alternate Names - Adenovirus E1A enhancer-binding protein
- E1A-F
- Polyomavirus enhancer activator 3 homolog
- Protein PEA3
- ETS translocation variant 4
背景信息 ETS translocation variant 4 protein, alternatively known as Adenovirus E1A enhancer-binding protein E1A-F, or Polyomavirus enhancer activator 3 homolog (PEA3), is encoded by the human gene named ETVA/E1AF/PEA3. ETV4 is a protein that is a transcriptional activator that was first recognized as such because it allowed for the expression of the adenovirus E1A gene upon infection. Today ETV4 has been shown to be active in a wide variety of biological processes from stem cell differentiation, to mammary gland and duct morphogenesis to motor neuron and axon guidance. ETV4 activity is regulated via the ERK/MAP signaling and a complex interplay of post-translation modifications such as sumoylation and ubiquitination. In cancers, ETV4 activates HIF and its subsequent proliferation genes and overexpression in prostate cells leads to oncogenesis. EMD-Millipore’s Anti-ETV4 mouse monoclonal antibody has been tested in western blot against K562 cell lysates as well as recombinantly expressed ETV4 protein. 产品信息 格式 Ascites 控制 - K562 cell lysate
演示 Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide. 应用 应用 Detect ETS translocation variant 4 protein using this mouse monoclonal antibody, Anti-ETV4 Antibody & clone 1A2G3 validated for use in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 Purified recombinant fragment of human ETV4 expressed in E. Coli. 克隆 1A2G3 宿主 Mouse 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody 基因符号 - PEA3
- ETV4
- E1AF
纯化方法 Unpurified UniProt编号 - P43268
产品使用声明 质量保证 Evaluated by Western Blotting in K562 cell lysate.
Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected ETV4 in K562 cell lysate.
Optimal working dilutions must be determined by end user.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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下一件merck millipore产品：merck millipore,默克密理博,SNAP2BHMB-K,SNAP i.d. 2.0 MultiBlot Holders (4.5 x 8.4 cm)
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