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merck millipore,默克密理博,MABC42,Anti-Pleiotrophin Antibody, clone 3B10
产品名称:Anti-Pleiotrophin Antibody, clone 3B10
产品型号:MABC42
This Anti-Pleiotrophin Antibody, clone 3B10 is validated for use in IH, WB for the detection of Pleiotrophin.
merck millipore,默克密理博,MABC42,Anti-Pleiotrophin Antibody, clone 3B10
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB, IHC M Purified Monoclonal Antibody 描述 产品目录编号 MABC42 Replaces MABD179 描述 Anti-Pleiotrophin Antibody, clone 3B10 Alternate Names - Heparin-binding growth factor 8
- pleiotrophin
- neurite growth-promoting factor 1
- Heparin-binding brain mitogen
- heparin binding growth factor 8
- Heparin-binding growth-associated molecule
- heparin affin regulatory protein
- Heparin-binding neurite outgrowth-promoting factor 1
- pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)
- Osteoblast-specific factor 1
背景信息 Pleiotrophin (PTN) also called Neurite Growth-promoting Factor 1 (NEGF1) or HARP (Heparin affin regulatory peptide) is a new member of the heparin-binding neurotrophic factor family. PTN plays an important role in development processess and promotion of neurite extension. During embryonic development, pleiotrophin is expressed in the central and peripheral nervous system, lung, kidney, gut and bone. Pleiotrophin is also expressed by several tumor cells and is thought to be involved in tumor angiogenesis. PTN initiates an angiogenic switch in different cancer models and acts as an angiogenic factor. PTN does this through an interaction with endothelial cells to initiate proliferation, migration, and tube formation. 产品信息 格式 Purified 控制 - Human placenta tissue lysate
演示 Purified mouse monoclonal IgG1κ in buffer containing PBS without 0.05% sodium azide. 应用 应用 This Anti-Pleiotrophin Antibody, clone 3B10 is validated for use in IH, WB for the detection of Pleiotrophin. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Immunohistochemistry Analysis: A 1:500 dilution from a previous lot detected Pleiotrophin in papillary squamous cell carcinoma tissue. 生物信息 免疫原品种 Recombinant protein corresponding to chicken Pleiotrophin. 克隆 3B10 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human Species Reactivity Note Demonstrated to react with human. 抗体类型 Monoclonal Antibody Entrez基因编号 - XP_416358
基因符号 - HARP
- OSF-1
- PTN
- NEGF1
- HBNF-1
- HBBM
- HBGF8
- HBGF-8
- HBNF1
- HB-GAM
纯化方法 Protein G Purified UniProt编号 - P32760
UniProt汇总 FUNCTION: Heparin binding mitogenic protein. Has neurite extension activity.
SUBCELLULAR LOCATION: Secreted.
SEQUENCE SIMILARITIES: Belongs to the pleiotrophin family.产品使用声明 质量保证 Evaluated by Western Blot in human placenta tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Pleiotrophin in 10 µg of human placenta tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 50 µg
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