merck millipore,默克密理愽
  • merck millipore,默克密理博,MABC148,Anti-Casper/c-FLIP Antibody, clone 17B12.1

  • merck millipore,默克密理博,MABC148,Anti-Casper/c-FLIP Antibody, clone 17B12.1

    产品名称：Anti-Casper/c-FLIP Antibody, clone 17B12.1
    产品型号：MABC148
    This Casper/c-FLIP antibody is validated for use in WB & IHC for the detection of the Casper/c-FLIP protein.

    merck millipore,默克密理博,MABC148,Anti-Casper/c-FLIP Antibody, clone 17B12.1

  • 产品介绍
  • merck millipore,默克密理博,MABC148,Anti-Casper/c-FLIP Antibody, clone 17B12.1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    H, RIHC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABC148
    描述 Anti-Casper/c-FLIP Antibody, clone 17B12.1
    Alternate Names
    • CASP8 and FADD-like apoptosis regulator subunit p43
    • CASP8 and FADD-like apoptosis regulator
    • Caspase homolog
    • CASH
    • Caspase-eight-related protein
    • Casper
    • Caspase-like apoptosis regulatory protein
    • CLARP
    • Cellular FLICE-like inhibitory protein
    • c-FLIP
    • FADD-like antiapoptotic molecule 1
    • FLAME-1
    • Inhibitor of FLICE
    • I-FLICE
    • MACH-related inducer of toxicity
    • MRIT
    • Usurpin
    • 2.CASP8 and FADD-like apoptosis regulator subunit p12
    背景信息 Caspase-eight-related protein (Casper), also known as Cellular FLICE-like inhibitory protein (c-FLIP), CASP8, FADD-like apoptosis regulator (CFLAR), Caspase homolog (CASH), Caspase-like apoptosis regulatory protein (CLARP), FADD-like antiapoptotic molecule 1 (FLAME-1), Inhibitor of FLICE (I-FLICE), MACH-related inducer of toxicity (MRIT), and Usurpin. Casper shows a wide expression profile, with higher expression in skeletal muscle, pancreas, heart, kidney, placenta, and peripheral blood leukocytes. Casper is an apoptosis regulator and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Casper lacks enzymatic activity.
    产品信息
    格式 Purified
    控制
    • PC-12 cell lysate
    演示 Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 This Casper/c-FLIP antibody is validated for use in WB & IHC for the detection of the Casper/c-FLIP protein.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Casper/c-FLIP in human cardiac myocytes tissue.
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to human Casper/c-FLIP.
    克隆 17B12.1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG2bκ
    品种反应性 HumanRat
    Species Reactivity Note Demonstrated to react with Rat and Human.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001120655
    基因符号
    • MRIT
    • CFLAR
    • CASH
    • CASP8AP1
    • CLARP
    纯化方法 Protein G purified
    UniProt编号
    • O15519
    产品使用声明
    质量保证 Evaluated by Western Blotting in PC-12 cell lysate.

    Western Blotting Analysis: 0.5 µg/mL of this antibody detected Casper/c-FLIP in 10 µg of PC-12 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABC148,Anti-Casper/c-FLIP Antibody, clone 17B12.1

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