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merck millipore,默克密理博,MABC13,Anti-TRAIL-R2 (CD262) Antibody, clone MD5-1
产品名称:Anti-TRAIL-R2 (CD262) Antibody, clone MD5-1
产品型号:MABC13
Anti-TRAIL-R2 (CD262) Antibody, clone MD5-1 is an antibody against TRAIL-R2 (CD262) for use in Flow Cytometry.
merck millipore,默克密理博,MABC13,Anti-TRAIL-R2 (CD262) Antibody, clone MD5-1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M FC Ht Purified Monoclonal Antibody 描述 产品目录编号 MABC13 描述 Anti-TRAIL-R2 (CD262) Antibody, clone MD5-1 Alternate Names - CD262
- Tumor necrosis factor receptor superfamily member 10B
- TRAIL-R2
- Death receptor 5
- MK
背景信息 TRAIL-R2 (CD262) is one of two pro-apoptotic receptors activated by the TNF-related apoptosis-inducing ligand (sTRAIL or Apo-2L). Ligand-bound TRAIL receptors form trimeric structures at the plasma membrane around a central zinc atom. The trimeric TRAIL receptors bind the FADD adaptor protein which in turn recruits caspase 8. TRAIL/APO-2L signals ultimately converge on caspase 3 and related proteins that promote cell death. Importantly, activated TRAIL receptors work cooperatively with death receptors 4 and 5 in transformed cells to induce caspase signaling, thereby preventing the proliferation of abnormal cells. TRAIL/ApO-2L has been implicated in pathophysiology of many disease processes, including cancer and autoimmune diseases. 产品信息 格式 Purified 控制 - NIH/3T3 cells
演示 Purified hamster monoclonal IgG in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-TRAIL-R2 (CD262) Antibody, clone MD5-1 is an antibody against TRAIL-R2 (CD262) for use in Flow Cytometry. 主要应用 - Flow Cytometry
生物信息 免疫原品种 Recombinant protein corresponding to mouse TRAIL-R2. 克隆 MD5-1 宿主 Hamster 同种型 IgG 品种反应性 Mouse Species Reactivity Note Demonstrated to react with Mouse. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_064671
基因符号 - Killer
- Tnfrsf10b
- Dr5
纯化方法 Protein G purified UniProt编号 - Q9QZM4
产品使用声明 质量保证 Evaluated by Flow Cytometry in NIH/3T3 cells.
Flow Cytometry Analysis: A 1:250 dilution of this antibody detected TRAIL-R2 in NIH/3T3 cells.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
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