merck millipore,默克密理博,540222,Puromycin, Dihydrochloride - CAS 58-58-2

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merck millipore,默克密理博,540222,Puromycin, Dihydrochloride - CAS 58-58-2 - Calbiochem
产品名称：Puromycin, Dihydrochloride - CAS 58-58-2 - Calbiochem
产品型号：540222
Protein synthesis inhibitor. Inhibits translation by causing premature release of nascent polypeptide chains. Induces DNA fragmentation in thymocytes and in human HL-60 leukemia cells.

merck millipore,默克密理博,540222,Puromycin, Dihydrochloride - CAS 58-58-2 - Calbiochem

产品介绍

merck millipore,默克密理博,540222,Puromycin, Dihydrochloride - CAS 58-58-2 - Calbiochem

重要规格表

经验配方	CAS号
C₂₂H₂₉N₇O₅ · 2HCl	58-58-2

描述
概述	Protein synthesis inhibitor. Inhibits translation by causing premature release of nascent polypeptide chains. Induces DNA fragmentation in thymocytes and in human HL-60 leukemia cells.
产品目录编号	540222
品牌系列	Calbiochem®
同义词	3ʹ-(α-Amino-p-methoxyhydrocinnamamido)-3ʹ-deoxy-N,N-dimethyladenosine, 2HCl

参考
参考	Chow, S.C., et al. 1995. Exp. Cell Res. 216, 149. Constam, D.B., et al. 1995. J. Biol. Chem. 270, 26931. Wirth, M., et al. 1994. J. Virol. 68, 566. Claeyssens, S., et al. 1993. FEBS Lett. 315, 7. Hechler, U., et al. 1993. Biochem. Biophys. Res. Commun. 194, 1305. Kaufman, S.H., et al. 1993. Cancer Res. 53, 3976. de la Luna, S. and Ortín, J. 1992. Methods Enzymol. 216, 376. Kalpaxis, D.L. and Drainas, D. 1992. Arch. Biochem. Biophys. 300, 629. Shipston, M.J. and Antoni, F.A. 1992. Biochem. Biophys. Res. Commun. 189, 1382.

参考

Chow, S.C., et al. 1995. Exp. Cell Res. 216, 149.
Constam, D.B., et al. 1995. J. Biol. Chem. 270, 26931.
Wirth, M., et al. 1994. J. Virol. 68, 566.
Claeyssens, S., et al. 1993. FEBS Lett. 315, 7.
Hechler, U., et al. 1993. Biochem. Biophys. Res. Commun. 194, 1305.
Kaufman, S.H., et al. 1993. Cancer Res. 53, 3976.
de la Luna, S. and Ortín, J. 1992. Methods Enzymol. 216, 376.
Kalpaxis, D.L. and Drainas, D. 1992. Arch. Biochem. Biophys. 300, 629.
Shipston, M.J. and Antoni, F.A. 1992. Biochem. Biophys. Res. Commun. 189, 1382.

产品信息
CAS号	58-58-2
形式	White to off-white solid
Hill配方	C₂₂H₂₉N₇O₅ · 2HCl
化学配方	C₂₂H₂₉N₇O₅ · 2HCl
Molar Mass	544.4
结构配方图像

生物信息
主靶	protein synthesis
纯度	≥98% by TLC

理化信息
溶解度	H₂O and MeOH

GHS安全信息
RTECS	AU7355000

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Harmful
储存	-20°C
防潮	Protect from moisture
无需冷冻	No
特殊指南	Following reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.