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merck millipore,默克密理博,MABC113,Anti-USP18 (UBP43) Antibody, clone 1C3.1
产品名称:Anti-USP18 (UBP43) Antibody, clone 1C3.1
产品型号:MABC113
This Anti-USP18 (UBP43) Antibody, clone 1C3.1 is validated for use in Western Blotting for the detection of USP18 (UBP43).
merck millipore,默克密理博,MABC113,Anti-USP18 (UBP43) Antibody, clone 1C3.1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H WB M Purified Monoclonal Antibody 描述 产品目录编号 MABC113 描述 Anti-USP18 (UBP43) Antibody, clone 1C3.1 Alternate Names - Ubl thioesterase 18
- Ubl carboxyl-terminal hydrolase 18
- 43 kDa ISG15-specific protease
- hUBP43
- ISG15-specific-processing protease
背景信息 The ubiqutin specific protease 18 (USP18; or UBP43) is a ubiquitin-specific protease that cleaves adducts of the ubiquitin-like modifier ISG15 from target substrates, and consequently regulates levels of the ISG15 protein. USP18 may be involved in multiple cellular processes including proliferation, inflammation, and stress responses. USP18 may also play an important role in innate immune responses to pathogenic organisms. Previous studies have reported that levels of ISG15-modified proteins increase after viral infection, and this is controlled by USP18. In addition, USP18 binds to type 1 INF receptors and inhibits their signaling by blocking their interaction with Jak2/STAT effector molecules, thereby downregulating INF signaling. 产品信息 格式 Purified 控制 - HepG2 cell lysate
演示 Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide. 应用 应用 This Anti-USP18 (UBP43) Antibody, clone 1C3.1 is validated for use in Western Blotting for the detection of USP18 (UBP43). 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human USP18 (UBP43). 克隆 1C3.1 宿主 Mouse 同种型 IgMκ 品种反应性 RatHuman Species Reactivity Note Demonstrated to react wtih Human and Rat. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_059110
基因符号 - ISG43
- USP18
纯化方法 Purified by ion-exchange chromatography UniProt编号 - Q9UMW8
产品使用声明 质量保证 Evaluated by Western Blot in HepG2 cell lysate.
Western Blot Analysis: A 1:2,000 dilution of this antibody detected USP18 (UBP43) in 10 µg of HepG2 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
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