• merck millipore,默克密理博,MABC113,Anti-USP18 (UBP43) Antibody, clone 1C3.1
  • merck millipore,默克密理博,MABC113,Anti-USP18 (UBP43) Antibody, clone 1C3.1

    产品名称:Anti-USP18 (UBP43) Antibody, clone 1C3.1
    产品型号:MABC113
    This Anti-USP18 (UBP43) Antibody, clone 1C3.1 is validated for use in Western Blotting for the detection of USP18 (UBP43).

    merck millipore,默克密理博,MABC113,Anti-USP18 (UBP43) Antibody, clone 1C3.1

  • 产品介绍
  • merck millipore,默克密理博,MABC113,Anti-USP18 (UBP43) Antibody, clone 1C3.1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABC113
    描述 Anti-USP18 (UBP43) Antibody, clone 1C3.1
    Alternate Names
    • Ubl thioesterase 18
    • Ubl carboxyl-terminal hydrolase 18
    • 43 kDa ISG15-specific protease
    • hUBP43
    • ISG15-specific-processing protease
    背景信息 The ubiqutin specific protease 18 (USP18; or UBP43) is a ubiquitin-specific protease that cleaves adducts of the ubiquitin-like modifier ISG15 from target substrates, and consequently regulates levels of the ISG15 protein. USP18 may be involved in multiple cellular processes including proliferation, inflammation, and stress responses. USP18 may also play an important role in innate immune responses to pathogenic organisms. Previous studies have reported that levels of ISG15-modified proteins increase after viral infection, and this is controlled by USP18. In addition, USP18 binds to type 1 INF receptors and inhibits their signaling by blocking their interaction with Jak2/STAT effector molecules, thereby downregulating INF signaling.
    产品信息
    格式 Purified
    控制
    • HepG2 cell lysate
    演示 Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
    应用
    应用 This Anti-USP18 (UBP43) Antibody, clone 1C3.1 is validated for use in Western Blotting for the detection of USP18 (UBP43).
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to human USP18 (UBP43).
    克隆 1C3.1
    宿主 Mouse
    同种型 IgMκ
    品种反应性 RatHuman
    Species Reactivity Note Demonstrated to react wtih Human and Rat.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_059110
    基因符号
    • ISG43
    • USP18
    纯化方法 Purified by ion-exchange chromatography
    UniProt编号
    • Q9UMW8
    产品使用声明
    质量保证 Evaluated by Western Blot in HepG2 cell lysate.

    Western Blot Analysis: A 1:2,000 dilution of this antibody detected USP18 (UBP43) in 10 µg of HepG2 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MABC113,Anti-USP18 (UBP43) Antibody, clone 1C3.1

上一件merck millipore产品:merck millipore,默克密理博,71727,pIEx/Bac™-4 DNA
下一件merck millipore产品:merck millipore,默克密理博,AB3067,Anti-Aquaporin 3 Antibody



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