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merck millipore,默克密理博,MAB5514,Anti-Choline Transporter Antibody, clone 62-2E8
产品名称：Anti-Choline Transporter Antibody, clone 62-2E8
产品型号：MAB5514
Detect Choline Transporter using this Anti-Choline Transporter Antibody, clone 62-2E8 validated for use in IC, IH & WB.
merck millipore,默克密理博,MAB5514,Anti-Choline Transporter Antibody, clone 62-2E8
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H WB, ICC, IHC M Ascites Monoclonal Antibody 描述 产品目录编号 MAB5514 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Choline Transporter Antibody, clone 62-2E8 Alternate Names - CHT
产品信息 格式 Ascites 演示 Ascites fluid. Liquid. Contains no preservative. 应用 应用 Detect Choline Transporter using this Anti-Choline Transporter Antibody, clone 62-2E8 validated for use in IC, IH & WB. 主要应用 - Western Blotting
- Immunocytochemistry
- Immunohistochemistry
应用说明 Western blot. The antibody detects a 65 kDa band in mouse brain tissue lysate. The CHT immunoreactivity was most abundant in the striatum.
Immunohistochemistry 1:2,000 - 1:8,000
Immunocytochemistry
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Recombinant protein from the C-terminus of human CHT. 克隆 62-2E8 宿主 Mouse 特异性 Hemicholinium-3-sensitive choline transporter (CHT). 同种型 IgG1 品种反应性 MouseHuman 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_021815.2
Entrez基因汇总 Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000 [PubMed 11027560]).[supplied by OMIM] 基因符号 - CHT
- SLC5A7
- MGC126299
- MGC126300
- CHT1
- hCHT
UniProt编号 - Q9GZV3
UniProt汇总 FUNCTION: SwissProt: Q9GZV3 # Imports choline from the extracellular space to the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. Sodium ion- and chloride ion- dependent.
SIZE: 580 amino acids; 63204 Da
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in putamen, spinal cord and medulla. Specific for cholinergic neurons.
PTM: Phosphorylated (By similarity).
SIMILARITY: SwissProt: Q9GZV3 ## Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
MISCELLANEOUS: Specifically inhibited by nanomolar concentrations of hemicholinium 3.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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