merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB416,Anti-Interferon-β Antibody, clone A1

  • merck millipore,默克密理博,MAB416,Anti-Interferon-β Antibody, clone A1

    产品名称：Anti-Interferon-β Antibody, clone A1
    产品型号：MAB416
    Anti-Interferon-β Antibody, clone A1 detects level of Interferon-β & has been published & validated for use in ELISA & WB.

    merck millipore,默克密理博,MAB416,Anti-Interferon-β Antibody, clone A1

  • 产品介绍
  • merck millipore,默克密理博,MAB416,Anti-Interferon-β Antibody, clone A1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWB, ELISAMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB416
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Interferon-β Antibody, clone A1
    产品信息
    格式 Purified
    演示 Immunoglobulin purified by Protein A from culture supernatant. Liquid in Phosphate Buffered Saline, pH 7.2
    应用
    应用 Anti-Interferon-β Antibody, clone A1 detects level of Interferon-β & has been published & validated for use in ELISA & WB.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Immunoblotting

    ELISA

    Neutralization of IFN-beta bioactivity; 90% reduction of bioactivity at 1.4 μg/mL for recombinant IFN-beta and 2.7 μg/mL for natural IFN-beta. Assay method used is provided in Grossberg, S.E. et al, Manual of Clinical Immunology.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Human interferon beta.
    克隆 A1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Human interferon-beta (IFN-beta). Recognizes amino acids 30-47 of IFN-beta. No cross-reactivity with Human IFN-alpha or IFN-gamma.
    同种型 IgGκ
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_000600.2
    基因符号
    • HGF
    • IL6
    • IL-6
    • HSF
    • BSF2
    • BSF-2
    • CDF
    • IFNB2
    UniProt编号
    • P05231
    UniProt汇总 FUNCTION: SwissProt: P05231 # IL-6 is a cytokine with a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, it induces nerve cells differentiation, in hepatocytes it induces acute phase reactants.
    SIZE: 212 amino acids; 23718 Da
    SUBCELLULAR LOCATION: Secreted.
    PTM: N- and O-glycosylated.
    DISEASE: SwissProt: P05231 # Genetic variations in IL6 are associated with susceptibility to systemic juvenile rheumatoid arthritis [MIM:604302]. Systemic juvenile rheumatoid arthritis is juvenile chronic arthritis associated with severe, debilitating, extraarticular features, and occasionally fatal complications. Despite medical treatment, many children still experience early joint destruction, necessitating surgical replacement. & At least 1 polymorphism in the IL6 gene renders HIV- infected men susceptible to Kaposi sarcoma [MIM:148000]. Kaposi sarcoma is a sarcoma of spindle cells mixed with angiomatous tissue. A relatively rare malignant skin tumor that results in multifocal purplish coloured papules or plaques that eventually form nodules. Most commonly seen in patients who suffer from AIDS.
    SIMILARITY: SwissProt: P05231 ## Belongs to the IL-6 superfamily.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to twelve months after date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB416,Anti-Interferon-β Antibody, clone A1

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