merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB4100,Anti-MRP1 Antibody, clone QCRL-1

  • merck millipore,默克密理博,MAB4100,Anti-MRP1 Antibody, clone QCRL-1

    产品名称：Anti-MRP1 Antibody, clone QCRL-1
    产品型号：MAB4100
    Anti-MRP1 Antibody, clone QCRL-1 detects level of MRP1 & has been published & validated for use in FC, WB, IC, IH, IH(P).

    merck millipore,默克密理博,MAB4100,Anti-MRP1 Antibody, clone QCRL-1

  • 产品介绍
  • merck millipore,默克密理博,MAB4100,Anti-MRP1 Antibody, clone QCRL-1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, FC, WB, ICCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB4100
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-MRP1 Antibody, clone QCRL-1
    Alternate Names
    • Multidrug Resistance Protein-1
    产品信息
    格式 Purified
    演示 Purified immunoglobulin. Liquid in PBS with 0.1% sodium azide.
    应用
    应用 Anti-MRP1 Antibody, clone QCRL-1 detects level of MRP1 & has been published & validated for use in FC, WB, IC, IH, IH(P).
    主要应用
    • Immunohistochemistry
    • Flow Cytometry
    • Western Blotting
    • Immunocytochemistry
    应用说明 Western Blot: 0.2 μg/mL, with HRP-conjugated anti mouse IgG (Hipfner et al., 1994, 1996).

    Immunocytochemistry: 1:20 - 1:50 on paraformaldehyde-fixed (0.5% in PBS) or 70% methanol-fixed cytospin preparations (Hipfner et al., 1999).

    Immunohistochemistry on formalin-fixed paraffini-embedded sections following antigen retrieval by microwave heating in citrate (Wright, et al., 1998).

    Flow cytometry: 1:20 dilution on cells fixed in 0.5% paraformaldehyde in PBS for 30 minutes, followed by anti-mouse FITC (block and wash with solution containing 0.1% Tween) (Hipfner, et al., 1994).

    Immunoprecipitation (Hipfner, et al., 1994; 1996).

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Non-denatured membranes prepared from the human small cell lung cancer cell line, H69AR, which highly overexpresses MRP1 (Cole et al., 1992; Hipfner et al., 1994, 1999).
    克隆 QCRL-1
    宿主 Mouse
    特异性 Reacts with a defined linear epitope (aa 918-924) of MRP1, a 190 kDa transmembrane

    phosphoglycoprotein overexpressed in various human multidrug resistant tumor cell lines

    and tumors (Cole et al., 1992; Hipfner et al., 1994, 1996, 1999; Wright et al, 1998). Does not cross react with the mouse mrp1, or human MDR1, MDR3,

    MRP2, MRP3, MRP4, MRP5 or MRP6 gene products.
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_019900.2
    • NM_019901.1
    • NM_019902.1
    • NM_004996.3
    • NM_019862.2
    • NM_019898.2
    • NM_019899.2
    Entrez基因汇总 The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
    基因符号
    • DKFZp686N04233
    • ABCC1
    • 4transporter)
    • ABC29
    • GS-X
    • ABCC
    • MRP1
    • DKFZp781G125
    • MRP
    UniProt编号
    • P33527
    UniProt汇总 FUNCTION: SwissProt: P33527 # May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Confers resistance to anticancer drugs. Transports LTC4. May protect milk against xenobiotics (By similarity).
    SIZE: 1531 amino acids; 171561 Da
    SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Lung, testis and peripheral blood mononuclear cells.
    SIMILARITY: SwissProt: P33527 ## Belongs to the ABC transporter family. Conjugate transporter (TC 3.A.1.208) subfamily. & Contains 2 ABC transmembrane type-1 domains. & Contains 2 ABC transporter domains.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store at 2-8ºC for up to 3 months. For longer term storage, aliquot and freeze at -20ºC.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB4100,Anti-MRP1 Antibody, clone QCRL-1

上一件merck millipore产品：merck millipore,默克密理博,14-570,Ret Protein, active, 10 µg
下一件merck millipore产品：merck millipore,默克密理博,AP114,Goat Anti-Human IgM Antibody, Fc5µ


相关产品

merck millipore,默克密理博,182707,AhR Antagonist III, GNF351 - Calbiochem merck millipore,默克密理博,182707,AhR Antagonist III, GNF351 - Calbiochem

merck millipore,默克密理博,07-875,Anti-phospho-PKCδ (Ser664) Antibody merck millipore,默克密理博,07-875,Anti-phospho-PKCδ (Ser664) Antibody

merck millipore,默克密理博,14-1102,Human Recombinant PRMT5 (Active Full Length) merck millipore,默克密理博,14-1102,Human Recombinant PRMT5 (Active Full Length)

merck millipore,默克密理博,04-035,Anti-PTEN Antibody, clone 6H2.1 merck millipore,默克密理博,04-035,Anti-PTEN Antibody, clone 6H2.1

merck millipore,默克密理博,14-570,Ret Protein, active, 10 µg merck millipore,默克密理博,14-570,Ret Protein, active, 10 µg

merck millipore,默克密理博,AP114,Goat Anti-Human IgM Antibody, Fc5µ merck millipore,默克密理博,AP114,Goat Anti-Human IgM Antibody, Fc5µ

merck millipore,默克密理博,14-792,PI 3-Kinase (p110α(H1047R)/p85α), 10 µg merck millipore,默克密理博,14-792,PI 3-Kinase (p110α(H1047R)/p85α), 10 µg

merck millipore,默克密理博,WBLUF0100,Luminata Forte Western HRP substrate, 100 mL merck millipore,默克密理博,WBLUF0100,Luminata Forte Western HRP substrate, 100 mL

merck millipore,默克密理博,CC1028,ADAMTS-4, recombinant, His Tagged merck millipore,默克密理博,CC1028,ADAMTS-4, recombinant, His Tagged

merck millipore,默克密理博,70939,pET-43.1a(+) DNA - Novagen merck millipore,默克密理博,70939,pET-43.1a(+) DNA - Novagen


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部