merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB396,Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11

  • merck millipore,默克密理博,MAB396,Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11

    产品名称：Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11
    产品型号：MAB396
    Detect Glutamate Receptor 2 & 4 using this Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11 validated for use in ELISA, IC, IH, IP, RIA & WB.

    merck millipore,默克密理博,MAB396,Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11

  • 产品介绍
  • merck millipore,默克密理博,MAB396,Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MkWB, ELISA, ICC, IHCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB396
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11
    Alternate Names
    • GluR2/4
    产品信息
    格式 Purified
    演示 Purified immunoglobulin. Liquid in PBS, no preservative.
    应用
    应用 Detect Glutamate Receptor 2 & 4 using this Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11 validated for use in ELISA, IC, IH, IP, RIA & WB.
    主要应用
    • Western Blotting
    • ELISA
    • Immunocytochemistry
    • Immunohistochemistry
    应用说明 Immunohistochemistry on 4% paraformaldehyde fixed

    tissue: 1:500-1,000

    Immunocytochemistry

    ELISA

    RIA

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Recombinant fusion protein TrpE-GluR2
    克隆 3A11
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Glutamate Receptor 2 (GluR2) by Western blot and RIA. When using MAB396 for immunohistochemistry or immunoprecipitation it recognizes both GluR2 and GluR4.
    同种型 IgG2a
    品种反应性 RatHumanMonkey
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_000839.2
    Entrez基因汇总 L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
    基因符号
    • GLUR2
    • GRM2
    • mGlu2
    • GPRC1B
    • MGLUR2
    • mGluR2
    UniProt编号
    • Q14833
    • Q14416
    UniProt汇总 FUNCTION: SwissProt: Q14833 # Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.
    SIZE: 912 amino acids; 101868 Da
    SUBUNIT: Interacts with PRKCABP (By similarity).
    SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Strongly expressed in the cerebellum. Expressed at low levels in hippocampus, hypothalamus and thalamus. No expression detected in liver.
    SIMILARITY: SwissProt: Q14833 ## Belongs to the G-protein coupled receptor 3 family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up 12 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB396,Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11

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