merck millipore,默克密理博,MAB390-100UG,Anti-p75 LNGFR Antibody, Saporin conjugated, clone 192

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

当前位置：首页 > >Merck Millipore > 生命科学研究
生命科学研究

merck millipore,默克密理博,MAB390-100UG,Anti-p75 LNGFR Antibody, Saporin conjugated, clone 192
产品名称：Anti-p75 LNGFR Antibody, Saporin conjugated, clone 192
产品型号：MAB390-100UG
Anti-p75 Low Affinity Nerve Growth Factor Receptor Antibody, Saporin conjugated, clone 192 is an antibody against p75 Low Affinity Nerve Growth Factor Receptor for use in 0.

merck millipore,默克密理博,MAB390-100UG,Anti-p75 LNGFR Antibody, Saporin conjugated, clone 192

产品介绍

merck millipore,默克密理博,MAB390-100UG,Anti-p75 LNGFR Antibody, Saporin conjugated, clone 192

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R	IL	M	Saporin	Monoclonal Antibody

描述
产品目录编号	MAB390-100UG
品牌系列	Chemicon®
商名	Chemicon
描述	Anti-p75 LNGFR Antibody, Saporin conjugated, clone 192
Alternate Names	NGFR p75 Low Affinity Neurotrophin Receptor

产品信息
格式	Saporin
演示	Saporin Conjugated. 192-IgG-SAP is sterile filtered and presented in Dulbecco's PBS with no preservative.

应用
应用	Anti-p75 Low Affinity Nerve Growth Factor Receptor Antibody, Saporin conjugated, clone 192 is an antibody against p75 Low Affinity Nerve Growth Factor Receptor for use in 0.
主要应用	Immunolesioning
应用说明	Immunotoxin (see "Protocols" for Technical Notes)

生物信息
克隆	192
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	Rat NGF receptor. MAB365 is the monoclonal antibody used for MAB390-SAP
同种型	IgG1
品种反应性	Rat
抗体类型	Monoclonal Antibody
Entrez基因编号	NM_002507.2
Entrez基因汇总	Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.
基因符号	CD271 NGFR p75(NTR) TNFRSF16 Gp80-LNGFR
非反应性品种	Mouse Human
UniProt编号	P08138
UniProt汇总	FUNCTION: SwissProt: P08138 # Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. SIZE: 427 amino acids; 45183 Da SUBUNIT: Homodimer; disulfide-linked. Interacts with p75NTR- associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. DOMAIN: SwissProt: P08138 Death domain is responsible for interaction with RANBP9. PTM: N- and O-glycosylated. & O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc. & Phosphorylated on serine residues. SIMILARITY: Contains 1 death domain. & Contains 4 TNFR-Cys repeats.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Centrifuge material at low speed in microfuge to ensure all of the solution is at the bottom of the tube. Vortex gently. Long term storage at -70ºC or below. Short term storage at -20ºC or 2-8ºC with appropriate antibacterial agent if compatible with the intended application. The sterile conjugate is stable at 2-8ºC for several months. Avoid repeated freezing and thawing. Glycerol (1:1) can be added for additional stability if compatible with the intended application. This immunotoxin may be handled safely using standard laboratory procedures as the cross-species reactivity between these anti-rat p75 antibodies and the human form of p75 is negligible.

储存和货运信息

存储条件

Centrifuge material at low speed in microfuge to ensure all of the solution is at the bottom of the tube. Vortex gently. Long term storage at -70ºC or below. Short term storage at -20ºC or 2-8ºC with appropriate antibacterial agent if compatible with the intended application. The sterile conjugate is stable at 2-8ºC for several months. Avoid repeated freezing and thawing. Glycerol (1:1) can be added for additional stability if compatible with the intended application. This immunotoxin may be handled safely using standard laboratory procedures as the cross-species reactivity between these anti-rat p75 antibodies and the human form of p75 is negligible.