- 当前位置:首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-

-
merck millipore,默克密理博,MAB3478,Anti-1-cys Peroxiredoxin Antibody, clone 8H11
产品名称:Anti-1-cys Peroxiredoxin Antibody, clone 8H11
产品型号:MAB3478
Detect 1-cys Peroxiredoxin using this Anti-1-cys Peroxiredoxin Antibody, clone 8H11 validated for use in WB, IC, IH.
merck millipore,默克密理博,MAB3478,Anti-1-cys Peroxiredoxin Antibody, clone 8H11
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H IHC, WB, ICC M Ascites Monoclonal Antibody 描述 产品目录编号 MAB3478 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-1-cys Peroxiredoxin Antibody, clone 8H11 Alternate Names - Non-selenium Glutathione Peroxidase
- Peroxiredoxin 6
- aiPLA2
背景信息 1-Cys-Peroxiredoxin is a cytosolic protein that is involved in the regulation of cellular redox potential. 1-Cys peroxiredoxin is a bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities (Chen, 2000). It can reduce hydrogen peroxide, short chain fatty acids, and phospholipid hydroperoxides and is believed to play a role in phospholipid turnover as well as in the protection against oxidative injury. 产品信息 格式 Ascites 演示 Ascites fluid. Liquid. 应用 应用 Detect 1-cys Peroxiredoxin using this Anti-1-cys Peroxiredoxin Antibody, clone 8H11 validated for use in WB, IC, IH. 主要应用 - Immunohistochemistry
- Western Blotting
- Immunocytochemistry
应用说明 Western blot on rat lung lysate (24 kDa) or recombinant human protein.
Immunohistochemistry on 4% paraformaldehyde fixed rat lung tissue.
Immunocytochemistry on rat type II alveolar epithelial cells.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Recombinant human 1-Cys peroxiredoxin. 克隆 8H11 宿主 Mouse 特异性 1-Cys-Peroxiredoxin (Prx VI). 同种型 IgM 品种反应性 RatHuman 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_004905.2
Entrez基因汇总 The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. 基因符号 - EC 1.11.1.7
- PRDX6
- p29
- Peroxiredoxin-6
- MGC46173
- PRX
- aiPLA2
- AOP2
- 1-Cys
- KIAA0106
- NSGPx
- EC 1.11.1.15
- EC 3.1.1.-
UniProt编号 - P30041
UniProt汇总 FUNCTION: SwissProt: P30041 # Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
SIZE: 224 amino acids; 25035 Da
SUBUNIT: Homotetramer. May interact with HTR2A (By similarity). Interacts with STH.
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Lysosome (By similarity). Cytoplasmic vesicle (By similarity). Note=And also found in lung secretory organelles (By similarity).
SIMILARITY: SwissProt: P30041 ## Belongs to the ahpC/TSA family. Rehydrin subfamily.
MISCELLANEOUS: The active site is the redox-active Cys-47 oxidized to Cys-SOH. Cys-SOH may rapidly react with a Cys-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin. & Irreversibly inactivated by overoxidation of Cys-47 (to Cys-SO(3)H) upon oxidative stress.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
上一件merck millipore产品:merck millipore,默克密理博,69863,pET-27b(+) DNA - Novagen
下一件merck millipore产品:merck millipore,默克密理博,AB9326,Anti-Transient Receptor Potential Channel 7 Antibody, pain
merck millipore,默克密理博,14-429,MEK1 Protein, active, 10 µg
merck millipore,默克密理博,17-10082,PureEpi™ Chromatin Preparation and Optimization Kit
merck millipore,默克密理博,553571,Anti-Ras (31-43) Rabbit pAb
merck millipore,默克密理博,SF-2052,FANCC; Human, Cyanine 5 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,69863,pET-27b(+) DNA - Novagen
merck millipore,默克密理博,AB9326,Anti-Transient Receptor Potential Channel 7 Antibody, pain
merck millipore,默克密理博,481486,NF-κB SN50M, Cell-Permeable Inactive Control Peptide - Calbiochem
merck millipore,默克密理博,71149,pETcoco™-2 System - Novagen
merck millipore,默克密理博,ST1689,Anti-FCN2 Rabbit pAb
merck millipore,默克密理博,05-480,Anti-Eck/EphA2 Antibody, clone D7


