• merck millipore,默克密理博,MAB3478,Anti-1-cys Peroxiredoxin Antibody, clone 8H11
  • merck millipore,默克密理博,MAB3478,Anti-1-cys Peroxiredoxin Antibody, clone 8H11

    产品名称:Anti-1-cys Peroxiredoxin Antibody, clone 8H11
    产品型号:MAB3478
    Detect 1-cys Peroxiredoxin using this Anti-1-cys Peroxiredoxin Antibody, clone 8H11 validated for use in WB, IC, IH.

    merck millipore,默克密理博,MAB3478,Anti-1-cys Peroxiredoxin Antibody, clone 8H11

  • 产品介绍
  • merck millipore,默克密理博,MAB3478,Anti-1-cys Peroxiredoxin Antibody, clone 8H11

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HIHC, WB, ICCMAscitesMonoclonal Antibody
    描述
    产品目录编号 MAB3478
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-1-cys Peroxiredoxin Antibody, clone 8H11
    Alternate Names
    • Non-selenium Glutathione Peroxidase
    • Peroxiredoxin 6
    • aiPLA2
    背景信息 1-Cys-Peroxiredoxin is a cytosolic protein that is involved in the regulation of cellular redox potential. 1-Cys peroxiredoxin is a bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities (Chen, 2000). It can reduce hydrogen peroxide, short chain fatty acids, and phospholipid hydroperoxides and is believed to play a role in phospholipid turnover as well as in the protection against oxidative injury.
    产品信息
    格式 Ascites
    演示 Ascites fluid. Liquid.
    应用
    应用 Detect 1-cys Peroxiredoxin using this Anti-1-cys Peroxiredoxin Antibody, clone 8H11 validated for use in WB, IC, IH.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    • Immunocytochemistry
    应用说明 Western blot on rat lung lysate (24 kDa) or recombinant human protein.

    Immunohistochemistry on 4% paraformaldehyde fixed rat lung tissue.

    Immunocytochemistry on rat type II alveolar epithelial cells.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Recombinant human 1-Cys peroxiredoxin.
    克隆 8H11
    宿主 Mouse
    特异性 1-Cys-Peroxiredoxin (Prx VI).
    同种型 IgM
    品种反应性 RatHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_004905.2
    Entrez基因汇总 The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
    基因符号
    • EC 1.11.1.7
    • PRDX6
    • p29
    • Peroxiredoxin-6
    • MGC46173
    • PRX
    • aiPLA2
    • AOP2
    • 1-Cys
    • KIAA0106
    • NSGPx
    • EC 1.11.1.15
    • EC 3.1.1.-
    UniProt编号
    • P30041
    UniProt汇总 FUNCTION: SwissProt: P30041 # Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
    SIZE: 224 amino acids; 25035 Da
    SUBUNIT: Homotetramer. May interact with HTR2A (By similarity). Interacts with STH.
    SUBCELLULAR LOCATION: Cytoplasm (By similarity). Lysosome (By similarity). Cytoplasmic vesicle (By similarity). Note=And also found in lung secretory organelles (By similarity).
    SIMILARITY: SwissProt: P30041 ## Belongs to the ahpC/TSA family. Rehydrin subfamily.
    MISCELLANEOUS: The active site is the redox-active Cys-47 oxidized to Cys-SOH. Cys-SOH may rapidly react with a Cys-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin. & Irreversibly inactivated by overoxidation of Cys-47 (to Cys-SO(3)H) upon oxidative stress.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MAB3478,Anti-1-cys Peroxiredoxin Antibody, clone 8H11

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下一件merck millipore产品:merck millipore,默克密理博,AB9326,Anti-Transient Receptor Potential Channel 7 Antibody, pain



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