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品种反应性 主要应用 宿主 格式 抗体类型 H IHC, ELISA, WB, ICC M Ascites Monoclonal Antibody 描述 产品目录编号 MAB3084 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Calpastatin Antibody, clone PI-11 产品信息 格式 Ascites 演示 In 50 mM Imidazole buffer, pH 7.4 with 50% glycerol. Contains no preservative. 应用 应用 Anti-Calpastatin Antibody, clone PI-11 is an antibody against Calpastatin for use in ELISA, WB, IC, IH. 主要应用 - Immunohistochemistry
- ELISA
- Western Blotting
- Immunocytochemistry
应用说明 Immunoblot: 1:1,000
ELISA: 1:30,000 (against the immunogen)
Immunohistochemistry: 1:100 on 4% paraformaldehyde fixed tissue.
Immunocytochemistry: 1:100.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Human erythrocyte calpastatin. 克隆 PI-11 宿主 Mouse 特异性 Reacts with human calpastatin. 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_173063.1
- NM_001042440.1
- NM_001042441.1
- NM_001042442.1
- NM_001042443.1
- NM_001042444.1
- NM_001042445.1
- NM_001042446.1
- NM_001750.5
- NM_173060.2
- NM_173061.2
Entrez基因汇总 The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length natures of only some have been determined. 基因符号 - BS-17
- CAST
- calpastatin
- MGC9402
- Calpastatin
UniProt编号 - P20810
UniProt汇总 FUNCTION: SwissProt: P20810 # Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.
SIZE: 708 amino acids; 76573 Da
DOMAIN: SwissProt: P20810 Has four inhibitory domains.
PTM: The N-terminus is blocked. & Phosphorylated.
SIMILARITY: Belongs to the protease inhibitor I27 (calpastatin) family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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