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merck millipore,默克密理博,MAB2701,Anti-Prolyl 4-hydroxylase β Antibody, clone 3-2B12
产品名称：Anti-Prolyl 4-hydroxylase β Antibody, clone 3-2B12
产品型号：MAB2701
Detect Prolyl 4-hydroxylase β using this Anti-Prolyl 4-hydroxylase β Antibody, clone 3-2B12 validated for use in ELISA, WB, IH(P).
merck millipore,默克密理博,MAB2701,Anti-Prolyl 4-hydroxylase β Antibody, clone 3-2B12
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB, ELISA M Purified Monoclonal Antibody 描述 产品目录编号 MAB2701 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Prolyl 4-hydroxylase β Antibody, clone 3-2B12 产品信息 格式 Purified 演示 Purified immunoglobulin 应用 应用 Detect Prolyl 4-hydroxylase β using this Anti-Prolyl 4-hydroxylase β Antibody, clone 3-2B12 validated for use in ELISA, WB, IH(P). 主要应用 - Western Blotting
- ELISA
应用说明 Immunoblotting: 2.5 μg/mL
Immunohistochemistry on frozen and paraffin-embedded tissue sections: 20 μg/mL
ElA
Optimal working dilutions must be determined by the end user.生物信息 克隆 3-2B12 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 The antibody specifically reacts with the beta-subunit of hPH. This is a purified mouse monoclonal antibody to human prolyl 4-hydroxylase (hPH). 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_000918.3
Entrez基因汇总 This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. 基因符号 - EC 1.14.11.2
- P4HA1
- P4HA
UniProt编号 - P07237
UniProt汇总 FUNCTION: SwissProt: P13674 # Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
COFACTOR: Iron. & Ascorbate.
SIZE: 534 amino acids; 61049 Da
SUBUNIT: Heterotetramer of two alpha-1 chains and two beta chains (the beta chain is the multi-functional PDI).
SUBCELLULAR LOCATION: Endoplasmic reticulum lumen.
SIMILARITY: SwissProt: P13674 ## Contains 1 PKHD (prolyl/lysyl hydroxylase) domain. & Contains 1 TPR repeat.产品使用声明 销售限制 This product is not available for sale in Japan. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
- Manufactured by Daiichi Fine Chemical Co., Ltd
储存和货运信息 存储条件 Maintain frozen at -20°C in undiluted aliquots for up to 12 months. 包装信息 数量 100 µg
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