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品种反应性 主要应用 宿主 格式 抗体类型 Ch, H IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MAB2608 描述 Anti-Sidekick-2 Antibody, clone CS22 Alternate Names - chicken sidekick 2-like
- sidekick homolog 2 (chicken)
- Drosophila sidekick-like
- protein sidekick-2
背景信息 Protein sidekick-2 (Sdk-2) is a single-pass type-I membrane protein containing thirteen fibronectin type-III domains and six Ig-like C2-type domains. Sdk-2 is a homophilic, synaptic adhesion molecule that functions to upregulate retinal lamina-specific connectivity. Expression of Sdk-2 is observed in non-overlapping retinal neuron subsets and is concentrated at synapses that connect Sdk-expressing partners, both postsynaptic and presynaptic. 产品信息 格式 Purified 控制 - Y79 cell lysate
演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect Sidekick-2 using this Anti-Sidekick-2 Antibody, clone CS22 validated for use in WB, IH. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH. (Yamagata, M., et al. (2010). The Journal of Neuroscience. 30(10):3579-3588.) 生物信息 免疫原品种 Histidine-tagged recombinant protein corresponding to chicken Sidekick-2. 克隆 CS22 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 ChickenHuman Species Reactivity Note Demonstrated to react with human.
Predicted to react with chicken based on 100% sequence homology.抗体类型 Monoclonal Antibody Entrez基因编号 - NP_989869
基因符号 - SDK2
纯化方法 Protein G Purified UniProt编号 - Q8AV57
UniProt汇总 FUNCTION: Synaptic adhesion molecule that promotes lamina-specific connectivity in the retina.
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein (Potential). Cell junction › synapse (Potential).
TISSUE SPECIFICTY: Expressed by non-overlapping subsets of retinal neurons. Concentrated at synapses.
SEQUENCE SIMILARITIES: Contains 13 fibronectin type-III domains.
Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
Sequence caution The sequence AAN15076.1 differs from that shown. Reason: Erroneous initiation.产品使用声明 质量保证 Evaluated by Western Blot in Y79 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Sidekick-2 in 10 µg of Y79 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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