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经验配方 C₁₇H₂₂N₂O₅S₂ 描述 概述 A cell-permeable, diaryl sulfonamide PPARβ/δ subtype-specific pure competitive antagonist with an IC50 of 98 nM. Antagonizes ligand binding without enabling coregulator interactions. Inhibits the PPARβ/δ specific agonist-induced transcriptional activity in cell cultures. 产品目录编号 516569 品牌系列 Calbiochem®
同义词 PPARβ Antagonist II, methyl 3-(N-(4-(tert-butylamino)-2-methoxyphenyl)sulfamoyl)thiophene-2-carboxylate, PPARδ Antagonist II 参考 参考 Naruhn, S., et al. 2011, Mol. Pharm. 80, 828. 产品信息 形式 Dark yellow solid Hill配方 C₁₇H₂₂N₂O₅S₂ 化学配方 C₁₇H₂₂N₂O₅S₂ 结构配方图像 生物信息 纯度 ≥98% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
毒性 Standard Handling
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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