- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB M Ascites Monoclonal Antibody 描述 产品目录编号 MAB1763 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Fibulin-3 Antibody Alternate Names - EFEMP1
背景信息 Fibulin-3 is a protein that belongs to a family of extracellular proteins expressed in the basement membranes of blood vessels and the gene that encodes fibulin 3 is EFEMP1. It is a secreted protein that is present in serum, urine and tissue samples. A single mutation in FBLN3 is responsible for an autosomal dominant form of macular degeneration (Marmorstein, et al., 2002) 产品信息 格式 Ascites 控制 - Positive: ARPE-19 cell line.
演示 Ascites containg no preservatives. 应用 应用 This Anti-Fibulin-3 Antibody is validated for use in WB for the detection of Fibulin-3. 主要应用 - Western Blotting
应用说明 Western blot: 1:100 after immunoprecipitation 生物信息 免疫原品种 GST-tagged fibulin-3 fusion protein containing amino acids 107-493. 表位 amino acids 107-493 克隆 G3-5 宿主 Mouse 特异性 Clone G3-5 recognizes human fibulin-3 with a MW of 55 kDa. 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_004105.3
- NM_001039348.1
- NM_001039349.1
Entrez基因汇总 This gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Alternative splice patterns in the 5' UTR result in three transcript variants encoding the same extracellular matrix protein. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. 基因符号 - MTLV
- EFEMP1
- FBNL
- MLVT
- FBLN3
- FLJ35535
- DRAD
- fibrillin-like
- Fibulin-3
- S1-5
- FIBL-3
- MGC111353
- DHRD
UniProt编号 - Q12805
UniProt汇总 SIZE: 493 amino acids; 54641 Da
SUBCELLULAR LOCATION: Secreted.
DISEASE: SwissProt: Q12805 # Defects in EFEMP1 are a cause of Doyne honeycomb retinal dystrophy (DHRD) [MIM:126600]; also known as malattia leventinese (MLVT OR ML). DHRD is an autosomal dominant disease characterized by yellow-white deposits known as drusen that accumulate beneath the retinal pigment epithelium.
SIMILARITY: SwissProt: Q12805 ## Belongs to the fibulin family. & Contains 6 EGF-like domains.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C for up to 12 months from date of receipt in undiluted aliquots. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
上一件merck millipore产品：merck millipore,默克密理博,HTS176M,ChemiSCREEN™ Membrane Preparation Recombinant Human S1P1 Lysophospholipid Receptor
下一件merck millipore产品：merck millipore,默克密理博,ABC842,Anti-DR6 Antibody
相关产品
merck millipore,默克密理博,MAB5294-30UL,Anti-Neurofilament 70 kDa Antibody, clone DP5 2.7.3
merck millipore,默克密理博,LP4,Lipoprotein Deficient Serum, human
merck millipore,默克密理博,ECM810,In Vitro Osteogenesis Assay Kit
merck millipore,默克密理博,ABC842,Anti-DR6 Antibody
merck millipore,默克密理博,IF02L,Anti-Desmin (Ab-1) Mouse mAb (DE-B-5)
merck millipore,默克密理博,MABC260,Anti-TRAF1 Antibody, clone 1F3
merck millipore,默克密理博,04-365,Anti-IKK alpha Antibody, clone Y463,, rabbit monoclonal
merck millipore,默克密理博,14-744M,Haspin Protein, active, 250 µg