merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB1680-C,Anti-Filamin A Antibody, clone TI10, Ascites Free

  • merck millipore,默克密理博,MAB1680-C,Anti-Filamin A Antibody, clone TI10, Ascites Free

    产品名称：Anti-Filamin A Antibody, clone TI10, Ascites Free
    产品型号：MAB1680-C
    This Anti-Filamin A Antibody, clone TI10, Ascites Free is validated for use in western blotting, IHC, IP, flow cytometry, immunofluorescence & ICC for the detection of Filamin A.

    merck millipore,默克密理博,MAB1680-C,Anti-Filamin A Antibody, clone TI10, Ascites Free

  • 产品介绍
  • merck millipore,默克密理博,MAB1680-C,Anti-Filamin A Antibody, clone TI10, Ascites Free

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HICC, WB, IHC, FCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB1680-C
    描述 Anti-Filamin A Antibody, clone TI10, Ascites Free
    Alternate Names
    • Non-muscle filamin
    • Filamin-A
    • FLN-A
    • Actin-binding protein 280
    • ABP-280
    • Alpha-filamin
    • Endothelial actin-binding protein
    • Filamin-1
    背景信息 Filamin is a structural protein that forms flexible cross-links between two actin filaments. Filamin is a homodimer of polypeptide chains each joined to the other at one end with an actin binding site ath the other. It is present in smooth muscle, fibroblasts, platelets and lymphocytes.
    产品信息
    格式 Purified
    演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 This Anti-Filamin A Antibody, clone TI10, Ascites Free is validated for use in western blotting, IHC, IP, flow cytometry, immunofluorescence & ICC for the detection of Filamin A.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    • Immunohistochemistry
    • Flow Cytometry
    应用说明 Immunohistochemistry Analysis: A 1:50 and 1:500 dilution from a representative lot detected Filamin A in human prostate and kidney tissues, respectively.

    Immunohistochemistry Analysis: A representative lot from an independent laboratory detected Filamin A in human tumor tissue sections (Bedolla, R. G., et al. (2009). Clin Cancer Research. 15(3):788-796.).

    Western Blotting Analysis: A representative lot from an independent laboratory detected Filamin A in human normal and tumor tissue lysates (Bedolla, R. G., et al. (2009). Clin Cancer Research. 15(3):788-796.).

    Immunoprecipitation/Western Blotting Analysis: A representative lot from an independent laboratory immunoprecipitated Filamin A from transfected HEK293T cell lysates. The immunoprecipitated sample was then subjected to Western Blotting using the same lot of antibody (Nakagawa, K., et al. (2010). Biochem. J. 427(2):237–245.).

    Western Blotting Analysis: A representative lot from an independent laboratory detected Filamin A in transfected U937 cell lysate (Beekman, J. M., et al. (2008). J Immunol. 180(6):3938-3945.).

    Western Blotting Analysis: A representative lot from an independent laboratory detected Filamin A in prostate cancer cell lysate. (Lin, J., et al. (2007). Int. J. Cancer. 121(12):2596–2605.).

    Western Blotting Analysis: A representative lot from an independent laboratory detected Filamin A in LNCap and C4-2 whole cell lysates (Wang, Y., et al. (2007). Oncogene. 26(41):6061–6070.).

    Western Blotting Analysis: A representative lot from an independent laboratory detected pulled-down human Filamin A proteins. (Lad, Y., et al. (2007). EMBO J. 26(17):3993–4004.).

    Western Blotting Analysis: A representative lot from an independent laboratory detected Filamin A in lysate samples from normal bladder mucosa and muscle invasive bladder tumor (Smith, S. C., et al. (2007). Clin Cancer Res. 13(13):3803-3813.).

    Western Blotting Analysis: A representative lot from an independent laboratory detected Filamin A in lysate samples from human prefontal cortical tissue (Koh, P. O., et al. (2003). Ach Gen Psychiatry. 60(3):311-319.).

    Flow Cytometry Analysis: A representative lot from an independent laboratory detected Filamin A in transfected U937 cells (Beekman, J. M., et al. (2008). J Immunol. 180(6):3938-3945.).

    Flow Cytometry Analysis: A representative lot from an independent laboratory detected Filamin A in LAN-1 cells (Bachmann, A. S., et al. (2006) Cancer Sci. 97(12):1359–1365.).

    Immunofluorescence Analysis: A representative lot from an independent laboratory detected Filamin A in clinical patient samples (Kley, R. A., et al. (2007). Brain. 130(Pt 12):3250-3264.).

    Immunocytochemistry Analysis: A representative lot from an independent laboratory detected Filamin A in LAN-1 cells (Bachmann, A. S., et al. (2006) Cancer Sci. 97(12):1359–1365.).
    生物信息
    免疫原品种 Human platelet protein corresponding to human Filamin A.
    克隆 TI10
    浓缩 1 mg/mL
    宿主 Mouse
    特异性 This antibody recognizes Filamin A (actin-binding protein), both the unprocessed form (270-280 kDa), and the C-terminal (90-100 kDa) calpain cleavage fragment of Filamin A (Aakhus, 1992).
    同种型 IgG1κ
    品种反应性 Human
    Species Reactivity Note Human. Predicted to react with Bovine based on 100% sequence homology.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP-001104026
    基因符号
    • FLN1
    • FLNA
    • FNL
    纯化方法 Protein G purified
    UniProt编号
    • P21333
    产品使用声明
    质量保证 Evaluated by Western Blotting in human uterus tissue lysate.

    Western Blotting Analysis: 0.5 µg/mL of this antibody detected Filamin A in 10 µg of human uterus tissue lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB1680-C,Anti-Filamin A Antibody, clone TI10, Ascites Free

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