- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Po, Ch, H IHC M Purified Monoclonal Antibody 描述 产品目录编号 MAB1671 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Villin Antibody, clone ID2C3 产品信息 格式 Purified 演示 Liquid in PBS with 1 mg/mL BSA, no preservatives. 应用 应用 Anti-Villin Antibody, clone ID2C3 detects level of Villin & has been published & validated for use in IH. 主要应用 - Immunohistochemistry
应用说明 Immunohistochemistry at 1:50 to 1:100 frozen and paraffin embedded tissue sections.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Purified chicken villin 克隆 ID2C3 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 Porcine villin, chicken villin and villin from cellular extract of the intestinal cell line HT29 and human renal epithelial cells. Recognizes an antigen of molecular weight 58 kDa by immunoblot.
Useful in the investigation on the differentiation of "brush border" epithelia. Also useful for studies of gastrointestinal cells in normal and tumoral tissue and cellular origin in human renal cell carcinoma.同种型 IgG1 品种反应性 PigChickenHuman 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_007127.1
Entrez基因汇总 This gene encodes a member of a family of calcium-regulated actin-binding proteins. This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments. Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon. 基因符号 - Villin-1.
- VIL1
- VIL
- D2S1471
UniProt编号 - P09327
UniProt汇总 FUNCTION: SwissProt: P09327 # Ca(2+)-regulated actin-binding protein.
SIZE: 827 amino acids; 92695 Da
SUBUNIT: Monomer.
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
TISSUE SPECIFICITY: Major component of microvilli of intestinal epithelial cells and kidney proximal tubule cells.
DOMAIN: SwissProt: P09327 Consists of a large core fragment, the N-terminal portion, and a small headpiece, the C-terminal portion. The headpiece binds F-actin strongly in both the presence and absence of calcium.
SIMILARITY: Belongs to the villin/gelsolin family. & Contains 6 gelsolin-like repeats. & Contains 1 HP (headpiece) domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,MABF301,Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1
下一件merck millipore产品：merck millipore,默克密理博,S7110,ApopTag Fluorescein In Situ Apoptosis Detection Kit
相关产品
merck millipore,默克密理博,126615,Albumin, Bovine Serum, 10% Aqueous Solution, Nuclease-Free
merck millipore,默克密理博,SCGVU11RE,Stericup-GV，0.22 µm，PVDF，1000/1000 mL，射线灭菌
merck millipore,默克密理博,MABE480,Anti-Bmi-1 Antibody, clone EPR3745(2), rabbit monoclonal
merck millipore,默克密理博,AP503P,Goat Anti-Mouse IgG γ chain Antibody, HRP conjugate, Species Adsorbed
merck millipore,默克密理博,MABF301,Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1
merck millipore,默克密理博,S7110,ApopTag Fluorescein In Situ Apoptosis Detection Kit
merck millipore,默克密理博,12-350,GST
merck millipore,默克密理博,ABC243,Anti-AKR1B10 Antibody
merck millipore,默克密理博,APT139,Caspase 9 Colorimetric Activity Assay Kit, LEHD
