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merck millipore,默克密理博,MAB1578,Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2
产品名称：Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2
产品型号：MAB1578
Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2 detects level of Muscarinic Acetylcholine Receptor m4 & has been published & validated for use in IH, IP & WB.
merck millipore,默克密理博,MAB1578,Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Mk WB, IHC M Ascites Monoclonal Antibody 描述 产品目录编号 MAB1578 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2 产品信息 格式 Ascites 演示 Liquid in 0.02M Phosphate buffer, 0.25 M NaCl with 0.1% sodium azide. 应用 应用 Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2 detects level of Muscarinic Acetylcholine Receptor m4 & has been published & validated for use in IH, IP & WB. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Immunohistochemistry (monkey)
Western blot (transfected CHO cell lines)
Immunoprecipitation (rat and monkey)
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 m4 receptor i3 loop (human), fused to GST 克隆 18C7.2 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 m4 muscarinic acetylcholine receptor. No reactivity with the other subtypes. 同种型 IgG1 品种反应性 Monkey 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_000741.2
Entrez基因汇总 The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. 基因符号 - HM4
- CHRM4
UniProt编号 - P08173
UniProt汇总 FUNCTION: SwissProt: P08173 # The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.
SIZE: 479 amino acids; 53049 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: P08173 ## Belongs to the G-protein coupled receptor 1 family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months. 包装信息 数量 100 µL
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