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merck millipore,默克密理博,MAB002-68/7,Anti-Apolipoprotein C-III Antibody, clone 68/7
产品名称：Anti-Apolipoprotein C-III Antibody, clone 68/7
产品型号：MAB002-68/7
Detect Apolipoprotein C-III using this Anti-Apolipoprotein C-III Antibody, clone 68/7 validated for use in RIA.
merck millipore,默克密理博,MAB002-68/7,Anti-Apolipoprotein C-III Antibody, clone 68/7
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H RIA M Purified Monoclonal Antibody 描述 产品目录编号 MAB002-68/7 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Apolipoprotein C-III Antibody, clone 68/7 Alternate Names - ApoCIII
产品信息 格式 Purified 演示 Purified immunoglobulin. Liquid in 0.02 M Phosphate buffer,PH 7.6 0.25 M NaCl with 0.1% sodium azide. 应用 应用 Detect Apolipoprotein C-III using this Anti-Apolipoprotein C-III Antibody, clone 68/7 validated for use in RIA. 主要应用 - Radioimmunoassay
应用说明 Solid phase radioimmunoassay at 1:1,000, at 50% end point.
Optimal working dilutions must be determined by end user.生物信息 克隆 68/7 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 Apolipoprotein C-III. No reactivity to HDL, A2, VLDL, C2, LDL or AI. 同种型 IgG2a 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_000040.1
Entrez基因汇总 Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia. 基因符号 - MGC150353
- APOC3
- ApoC-III
- Apo-CIII
- APOCIII
UniProt编号 - P02656
UniProt汇总 FUNCTION: SwissProt: P02656 # Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles.
SIZE: 99 amino acids; 10852 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Constitutes 50% of the protein fraction of VLDL and 2% of that of HDL. Synthesized predominantly in liver and to a lesser degree in intestine.
PTM: O-linked glycan consists of Gal-GalNAc disaccharide, further modified with up to 3 sialic acid residues.
DISEASE:SwissProt: P02656 # Defects in APOC3 may be a cause of hyperalphalipoproteinemia [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
SIMILARITY: SwissProt: P02656 ## Belongs to the apolipoprotein C3 family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C in undiluted aliquots for up to six months. 包装信息 数量 500 µg
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