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merck millipore,默克密理博,IL005,Interleukin-5 Protein, Recombinant human
产品名称:Interleukin-5 Protein, Recombinant human
产品型号:IL005
The recombinant human Interleukin-5 protein (or IL-5 protein) is a potent T-cell derived factor which stimulates the growth of certain B-cells & the differentiation of eosinophils.
merck millipore,默克密理博,IL005,Interleukin-5 Protein, Recombinant human
- 产品介绍
重要规格表
主要应用 品种 纯度 CULT Human Greater than 98% by SDS-PAGE and HPLC analysis 描述 产品目录编号 IL005 品牌系列 Chemicon®
商名 - Chemicon
描述 Interleukin-5 Protein, Recombinant human 概述 Interleukin-5 (IL-5) is a potent T-cell derived factor which stimulates the growth of certain B-cells and the differentiation of eosinophils. Human IL-5 is a 26 kDa dimeric protein containing 232 amino acid residues. Alternate Names - IL-5
产品信息 演示 Lyophilized from 5 mM Tris, pH 7.2. 应用 应用 The recombinant human Interleukin-5 protein (or IL-5 protein) is a potent T-cell derived factor which stimulates the growth of certain B-cells & the differentiation of eosinophils. 主要应用 - Cell Culture
应用说明 For most in vitro applications, IL-5 exerts its biological activity in the concentration range of 0.1 to 10.0 ng/mL. Responding cells are (partial list): B-cells, eosinophils. 生物信息 纯度 Greater than 98% by SDS-PAGE and HPLC analysis 品种 Human 特异活性 Human IL-5 is fully biologically active when compared to standards. The ED50 as determined by the dose-dependent proliferation of TF-1 cells was less than 0.15 ng/mL, corresponding to a specific activity of > 6.6 x 10E6 units/mg. Entrez基因编号 - NM_000879.2
Entrez基因汇总 The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. 基因符号 - TRF
- IL5
- interleukin-5
- IL-5
- EDF
UniProt编号 - P05113
UniProt汇总 FUNCTION: SwissProt: P05113 # Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.
SIZE: 134 amino acids; 15238 Da
SUBUNIT: Homodimer; disulfide-linked.
SUBCELLULAR LOCATION: Secreted.
SIMILARITY: SwissProt: P05113 ## Belongs to the IL-5 family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 The lyophilized powder, though stable for a few weeks at room temperature, is best stored at -20°C. After a quick spin, reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into other aqueous buffers and stored at 4°C for one week or -20°C for future use. Reconstituted IL-5 should be stored in undiluted aliquots at -20°C for up to six months. 包装信息 数量 10 µg
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