merck millipore,默克密理愽
  • merck millipore,默克密理博,IL001,Interleukin-1α Protein, Recombinant human

  • merck millipore,默克密理博,IL001,Interleukin-1α Protein, Recombinant human

    产品名称：Interleukin-1α Protein, Recombinant human
    产品型号：IL001
    The recombinant human Interleukin-1alpha protein is a potent immuno-modulator which mediates a wide range of immune & inflammatory responses.

    merck millipore,默克密理博,IL001,Interleukin-1α Protein, Recombinant human

  • 产品介绍
  • merck millipore,默克密理博,IL001,Interleukin-1α Protein, Recombinant human

    重要规格表

    主要应用 品种 纯度
    CULTHumanGreater than 98% by SDS-PAGE and HPLC analyses.
    描述
    产品目录编号 IL001
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Interleukin-1α Protein, Recombinant human
    概述 Interleukin-1alpha is a potent immuno-modulator which mediates a wide range of immune and inflammatory responses. Human IL-1alpha is a 18.0 kDa protein containing 159 amino acid residues.
    Alternate Names
    • IL-1alpha
    产品信息
    演示 Lyophilized from 10 mM Tris, pH 8.0, containing 50 mM NaCl.
    应用
    应用 The recombinant human Interleukin-1alpha protein is a potent immuno-modulator which mediates a wide range of immune & inflammatory responses.
    主要应用
    • Cell Culture
    应用说明 For most in vitro applications, IL-1alpha exerts its biological activity in the concentration range of 0.1 to 10.0 ng/mL. Responding cells are (partial list): Leukocytes.
    生物信息
    纯度 Greater than 98% by SDS-PAGE and HPLC analyses.
    品种 Human
    特异活性 Human IL-1alpha is fully biologically active when compared to standards. The ED50 as determined by the dose-dependent stimulation of mouse D10S cells is less than 0.001 ng/mL, corresponding to a specific activity of >=1 x 10(E9) units/mg.
    Entrez基因编号
    • NM_000575.3
    Entrez基因汇总 The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
    基因符号
    • hematopoietin-1
    • IL1A
    • IL1-ALPHA
    • IL1
    • pro-interleukin-1-alpha
    • IL1F1
    • Hematopoietin-1
    • IL-1A
    UniProt编号
    • P01583
    UniProt汇总 FUNCTION: SwissProt: P01583 # Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
    SIZE: 271 amino acids; 30607 Da
    SUBUNIT: Monomer.
    SUBCELLULAR LOCATION: Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
    DOMAIN: SwissProt: P01583 The similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
    SIMILARITY: Belongs to the IL-1 family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 The lyophilized powder, though stable at room temperature, is best stored desiccated at -20°C. After a quick spin, reconstitute with sterile water to a concentration of 0.1-1 mg/mL. This solution can be diluted into other buffered solutions or stored at -20°C in undiluted aliquots for up to six months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 10 µg

    merck millipore,默克密理博,IL001,Interleukin-1α Protein, Recombinant human

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