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品种反应性 主要应用 宿主 格式 抗体类型 H IH(P) Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB9471 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Prostacyclin Receptor Antibody 产品信息 格式 Affinity Purified 演示 Affinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide. 应用 应用 Anti-Prostacyclin Receptor Antibody is an antibody against Prostacyclin Receptor for use in IH(P). 主要应用 - Immunohistochemistry (Paraffin)
应用说明 Immunohistochemistry on paraffin embedded tissue sections.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide from the N-terminal extracellular domain of human Prostacyclin Receptor. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes Prostacyclin Receptor. 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000960.3
Entrez基因汇总 The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. 基因符号 - IP
- PTGIR
- PRIPR
- MGC102830
UniProt编号 - P43119
UniProt汇总 FUNCTION: SwissProt: P43119 # Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
SIZE: 386 amino acids; 40956 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
PTM: Palmitoylation of either Cys-308 or Cys-311 is sufficient to maintain functional coupling to G(s) and signaling. & Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C.
SIMILARITY: SwissProt: P43119 ## Belongs to the G-protein coupled receptor 1 family.产品使用声明 销售限制 This product is not available for sale in Japan. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 50 µg
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