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merck millipore,默克密理博,FCMAB313PE,Milli-Mark Anti-Nestin-PE Antibody, clone 10C2
产品名称:Milli-Mark Anti-Nestin-PE Antibody, clone 10C2
产品型号:FCMAB313PE
Detect Nestin using this Milli-Mark Anti-Nestin-PE Antibody, clone 10C2 validated for use in FC.
merck millipore,默克密理博,FCMAB313PE,Milli-Mark Anti-Nestin-PE Antibody, clone 10C2
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC M Phycoerythrin Monoclonal Antibody 描述 产品目录编号 FCMAB313PE 商名 - Milli-Mark
描述 Milli-Mark® Anti-Nestin-PE Antibody, clone 10C2 背景信息 Nestin, a large intermediate filament protein (class Type VI) expressed during development and in myotendinous and neuromuscular junctions. Nestin expression is restricted, typically disappearing by E18. Nestin is thought to be a reasonable neuronal marker; however, recent studies have found nestin expression in other cell types such as endothelial cells {Folia Biologica, 44(5):155, 1998}. Nestin identifies the most primitive neuroepithelium but also identifies many other embryonic tissues, so it is not specific for CNS. Nestin expression is seen in almost all GBMs (Glioblastoma mulitformes) and many melanomas (both primary and metastatic) but not in any metastatic carcinoma. 产品信息 格式 Phycoerythrin 控制 - U251 cells
演示 Purified mouse monoclonal IgG1κ conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA. 应用 应用 Detect Nestin using this Milli-Mark Anti-Nestin-PE Antibody, clone 10C2 validated for use in FC. 主要应用 - Flow Cytometry
生物信息 免疫原品种 Fusion protein 表位 Human 克隆 10C2 宿主 Mouse 特异性 Antibody recognizes Human Nestin. 同种型 IgG1κ 品种反应性 Human Species Reactivity Note Tested and passed on human. No reactivity with mouse or rat Nestin. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_006608
Entrez基因汇总 Nestin is an intermediate filament protein that was first identified with a monoclonal antibody by Hockfield and McKay (1985) [PubMed 4078630]. It is expressed predominantly in stem cells of the central nervous system in the neural tube. Upon terminal neural differentiation, nestin is downregulated and replaced by neurofilaments. 基因符号 - Nbla00170
- NES
纯化方法 Protein A Purified UniProt编号 - P48681
UniProt汇总 FUNCTION: SwissProt: P48681 # May play a role in the trafficking and distribution of IF proteins and potentially other cellular factors to daughter cells during progenitor cell division (By similarity).
SIZE: 1621 amino acids; 177439 Da
SUBUNIT: Interacts with FHOD3 (By similarity).
TISSUE SPECIFICITY: CNS stem cells.
DEVELOPMENTAL STAGE: Upon terminal neural differentiation, nestin is down-regulated and replaced by neurofilaments.
SIMILARITY: SwissProt: P48681 ## Belongs to the intermediate filament family.产品使用声明 质量保证 Evaluated by flow cytometry using U251 cells. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt. 包装信息 数量 100 tests
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