• merck millipore,默克密理博,FCMAB286F,Milli-Mark™ Anti-ID4 Antibody, clone 10C6.2
  • merck millipore,默克密理博,FCMAB286F,Milli-Mark™ Anti-ID4 Antibody, clone 10C6.2

    产品名称:Milli-Mark™ Anti-ID4 Antibody, clone 10C6.2
    产品型号:FCMAB286F
    Milli-Mark Anti-ID4 Antibody, clone 10C6.2 is an antibody against ID4 for use in FC.

    merck millipore,默克密理博,FCMAB286F,Milli-Mark™ Anti-ID4 Antibody, clone 10C6.2

  • 产品介绍
  • merck millipore,默克密理博,FCMAB286F,Milli-Mark™ Anti-ID4 Antibody, clone 10C6.2

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HFCMFITCMonoclonal Antibody
    描述
    产品目录编号 FCMAB286F
    商名
    • Milli-Mark
    描述 Milli-Mark™ Anti-ID4 Antibody, clone 10C6.2
    背景信息 Id-4 is an inhibitor of differentiation protein, which, along with Id1, Id2 and Id3, plays a key role in the regulation of lineage commitment, cell fate decisions and in the timing of differentiation during neurogenesis, lymphopoiesis and neovascularisation (angiogenesis). Id proteins, induced by the bone morphogenic protein-SMAD pathway, have also been shown to collaborate with LIF to ensure that embryonic stem cells opt for self-renewal.
    产品信息
    格式 FITC
    控制
    • Mouse ES cells (CMTI-2)
    演示 Purified mouse monoclonal IgG2a conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA
    应用
    应用 Milli-Mark Anti-ID4 Antibody, clone 10C6.2 is an antibody against ID4 for use in FC.
    主要应用
    • Flow Cytometry
    生物信息
    免疫原品种 Recombinant GST Fusion protein (Human Id-4).
    克隆 10C6.2
    宿主 Mouse
    特异性 Antibody recognizes ID4.
    同种型 IgG2a
    品种反应性 Human
    Species Reactivity Note Tested and passed on Human.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001537
    Entrez基因汇总 Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al., 1995 [PubMed 7665172]).[supplied by OMIM]
    基因符号
    • ID4
    纯化方法 Protein A Purified
    UniProt编号
    • P47928
    UniProt汇总 FUNCTION: SwissProt: P47928 # ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding.

    SIZE: 161 amino acids; 16622 Da

    SUBUNIT: Heterodimer with other HLH proteins.

    SUBCELLULAR LOCATION: Nucleus.

    SIMILARITY: SwissProt: P47928 ## Contains 1 basic helix-loop-helix (bHLH) domain.
    产品使用声明
    质量保证 Evaluated by flow cytometry using mouse ES cells (CMTI-2)
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
    包装信息
    数量 100 tests

    merck millipore,默克密理博,FCMAB286F,Milli-Mark™ Anti-ID4 Antibody, clone 10C6.2

上一件merck millipore产品:merck millipore,默克密理博,MAB506S,Mouse Anti-Rat IgG2c γ2c chain Antibody, Cy5 conjugate
下一件merck millipore产品:merck millipore,默克密理博,MSHVN4510,MultiScreenHTS HV,0.45 µm,无色,非无菌



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