merck millipore,默克密理愽
  • merck millipore,默克密理博,FCMAB264F,Milli-Mark™ Anti-EpCam Antibody, FITC, clone mAB8

  • merck millipore,默克密理博,FCMAB264F,Milli-Mark™ Anti-EpCam Antibody, FITC, clone mAB8

    产品名称：Milli-Mark™ Anti-EpCam Antibody, FITC, clone mAB8
    产品型号：FCMAB264F
    Milli-Mark EpCam-FITC, clone mAB8 is an antibody targeting the Milli-Mark EpCam protein, validated for use in Flow.

    merck millipore,默克密理博,FCMAB264F,Milli-Mark™ Anti-EpCam Antibody, FITC, clone mAB8

  • 产品介绍
  • merck millipore,默克密理博,FCMAB264F,Milli-Mark™ Anti-EpCam Antibody, FITC, clone mAB8

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HFCMFITCMonoclonal Antibody
    描述
    产品目录编号 FCMAB264F
    商名
    • Milli-Mark
    描述 Milli-Mark™ Anti-EpCam Antibody, FITC, clone mAB8
    Alternate Names
    • tumor-associated calcium signal transducer 1
    • Adenocarcinoma-associated antigen
    • CD326 antigen
    • Cell surface glycoprotein Trop-1
    • Epithelial cell surface antigen
    • Epithelial glycoprotein
    • KS 1/4 antigen
    • Major gastrointestinal tumor-associated protein GA733-2
    • antigen identified by monoclonal antibody AUA1
    • carcinoma-associated antigen GA733-2
    • epithelial cell adhesion molecule
    • human epithelial glycoprotein-2
    • membrane component, chromosome 4, surface marker (35kD glycoprotein)
    背景信息 Epithelial Call Adhesion Molecule (EpCAM, CD326) is a transmembrane glycoprotein of approximately 40 kDa. EpCAM was initially identified as a tumor associated marker having high expression in quickly proliferating epithelial tumors. As such, EpCAM has been of significant interest as a means for tumor diagnosis and therapy. EpCAM is also expressed in normal epithelial cells, but in comparatively lower levels. Preliminary studies limited EpCAM’s function to cell-cell adhesion; however more recent studies indicate it to be involved in diverse processes that include cell migration, cell signaling, differentiation and proliferation.
    产品信息
    格式 FITC
    控制
    • 2102 Ep (human embryonal carcinoma cell line)
    演示 Purified mouse monoclonal IgG2a conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
    应用
    应用 Milli-Mark EpCam-FITC, clone mAB8 is an antibody targeting the Milli-Mark EpCam protein, validated for use in Flow.
    主要应用
    • Flow Cytometry
    生物信息
    免疫原品种 HES-3 cells (Choo et al., 2008)
    克隆 mAB8
    宿主 Mouse
    特异性 Antibody recognizes Epithelial Cell Adhesion Molecule (EpCAM).
    同种型 IgG2aκ
    品种反应性 Human
    Species Reactivity Note Tested and passed on Human.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_002345.2
    Entrez基因汇总 This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy
    基因符号
    • hEGP-2
    • EPCAM
    • 17-1A
    • 323/A3
    • CD326
    • CO-17A
    • CO17-1A
    • EGP
    • EGP-2
    • EGP34
    • EGP40
    • ESA
    • Ep-CAM
    • GA733-2
    • HEA125
    • KS1/4
    • KSA
    • Ly74
    • M1S2
    • M4S1
    • MH99
    • MIC18
    • MK-1
    • MOC31
    • TACST-1
    • TACSTD1
    • TROP1
    纯化方法 Protein G Purified
    UniProt编号
    • P16422
    UniProt汇总 FUNCTION: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection.

    SUBUNIT STRUCTURE: Monomer.

    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

    TISSUE SPECIFICTY: This protein is expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinomas.

    SEQUENCE SIMILARITIES: Belongs to the EPCAM family.
    产品使用声明
    质量保证 Evaluated by flow cytometry using 2102 Ep (human embryonal carcinoma cell line)
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.
    包装信息
    数量 100 tests

    merck millipore,默克密理博,FCMAB264F,Milli-Mark™ Anti-EpCam Antibody, FITC, clone mAB8

上一件merck millipore产品：merck millipore,默克密理博,219008,Catalase, Human Erythrocytes
下一件merck millipore产品：merck millipore,默克密理博,09-813,Anti-RING finger protein 8 Antibody


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