merck millipore,默克密理愽
  • merck millipore,默克密理博,14-680,HIPK3 Protein, active, 10 µg

  • merck millipore,默克密理博,14-680,HIPK3 Protein, active, 10 µg

    产品名称：HIPK3 Protein, active, 10 µg
    产品型号：14-680
    Active, N-terminal 6His-tagged, recombinant, human HIPK3, amino acids 161-562, for use in Kinase Assays.

    merck millipore,默克密理博,14-680,HIPK3 Protein, active, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-680,HIPK3 Protein, active, 10 µg

    描述
    产品目录编号 14-680
    品牌系列 Upstate
    商名
    • Upstate
    描述 HIPK3 Protein, active, 10 µg
    概述 N-terminal 6His-tagged, recombinant, human HIPK3, amino acids 161-562
    应用
    应用 Active, N-terminal 6His-tagged, recombinant, human HIPK3, amino acids 161-562, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 expressed by baculovirus in Sf21 cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
    Entrez基因编号
    • NM_005734.3
    • NM_001048200.1
    基因符号
    • FIST3
    • HIPK3
    • FIST
    • DYRK6
    • ANPK
    • PKY
    • YAK1
    蛋白靶 HIPK3
    纯化方法 Ni2+/NTA-agarose
    靶子系列 CMGC
    UniProt编号
    • Q9H422
    UniProt汇总 FUNCTION: SwissProt: Q9H422 # Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors.
    SIZE: 1215 amino acids; 133743 Da
    SUBUNIT: Interacts with Nkx1-2. Interacts with FAS and DAXX. Probably part of a complex consisting of HIPK3, FAS and FADD. Interacts with and stabilizes ligand-bound androgen receptor (AR) (By similarity). Interacts with UBL1/SUMO-1.
    SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
    TISSUE SPECIFICITY: Overexpressed in multidrug resistant cells. Highly expressed in heart and skeletal muscle, and at lower levels in placenta, pancreas, brain, spleen, prostate, thymus, testis, small intestine, colon and leukocytes. Not found in liver and lung.
    PTM: Autophosphorylated, but autophosphorylation is not required for catalytic activity (By similarity). & May be sumoylated (By similarity).
    SIMILARITY: SwissProt: Q9H422 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of MBP (Catalog # 13-104)
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable 6 months at -70°C from date of shipment
    包装信息
    数量 10 µg

    merck millipore,默克密理博,14-680,HIPK3 Protein, active, 10 µg

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