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merck millipore,默克密理博,FCMAB209F,Milli-Mark™ Anti-CD79β-FITC Antibody, clone SN8
产品名称:Milli-Mark™ Anti-CD79β-FITC Antibody, clone SN8
产品型号:FCMAB209F
Milli-Mark Anti-CD79β-FITC Antibody, clone SN8 detects level of CD79β & has been published & validated for use in FC.
merck millipore,默克密理博,FCMAB209F,Milli-Mark™ Anti-CD79β-FITC Antibody, clone SN8
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC M FITC Monoclonal Antibody 描述 产品目录编号 FCMAB209F 商名 - Milli-Mark
描述 Milli-Mark™ Anti-CD79β-FITC Antibody, clone SN8 Alternate Names - Immunoglobulin-associated B29 protein
- B-cell antigen receptor complex-associated protein beta chain
- Ig-beta
- B-cell-specific glycoprotein B29
背景信息 CD79beta is restricted to the B-cell lineage, and is found in pro-B cells before Ig heavy-chain gene rearrangement but after CD79alpha expression. The antibody reacts with an epitope on the extracellular domain of CD79 (Yoshida, 1995). Anti-CD79beta, SN8, was included in the Fifth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD79beta (Engel, 1995; Persin, 1995). 产品信息 格式 FITC 控制 - Human Lymphocytes
演示 Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2. 应用 应用 Milli-Mark Anti-CD79β-FITC Antibody, clone SN8 detects level of CD79β & has been published & validated for use in FC. 主要应用 - Flow Cytometry
生物信息 克隆 SN8 宿主 Mouse 特异性 Antibody recognizes Human CD79b antigen. 同种型 IgG1κ 品种反应性 Human Species Reactivity Note Tested and passed on Human. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_000617
Entrez基因汇总 The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. 纯化方法 Protein A Purified UniProt编号 - P40259
UniProt汇总 Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79B are a cause of hypogammaglobulinemia immunodeficiency and reduced B cells. Hypogammaglobulinemia is an immunologic deficiency state characterized by an extremely low level of generally all classes of gamma-globulin in the blood. The disorder results in a failure of B cell development in patients with immunodeficiency and is associated with a markedly reduced but not absent B cells. 产品使用声明 质量保证 Evaluated by flow cytometry using human lymphocytess 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt. 包装信息 数量 100 tests
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