merck millipore,默克密理愽
  • merck millipore,默克密理博,401490,IKK-2 Inhibitor XI - CAS 354810-80-3 - Calbiochem

  • merck millipore,默克密理博,401490,IKK-2 Inhibitor XI - CAS 354810-80-3 - Calbiochem

    产品名称：IKK-2 Inhibitor XI - CAS 354810-80-3 - Calbiochem
    产品型号：401490
    The IKK-2 Inhibitor XI, also referenced under CAS 354810-80-3, controls the biological activity of IKK-2. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.

    merck millipore,默克密理博,401490,IKK-2 Inhibitor XI - CAS 354810-80-3 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,401490,IKK-2 Inhibitor XI - CAS 354810-80-3 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₂H₁₁N₃O₂S354810-80-3
    描述
    概述 A cell-permeable thiophenecarboxamide-ureido compound that acts as a potent, ATP-binding pocket-targeting inhibitor of IKK-2 (IC50 = 25 nM), while affecting IKK-1 and JNK1 only at much higher concentrations (IC50 = 1.0 and 1.6 µM, respectively). Shown to reduce LPS-induced TNF-α production in PBMCs (IC50 = 250 nM) and exhibit oral availability with good pharmacokinetic in rats in vivo.
    产品目录编号 401490
    品牌系列 Calbiochem®
    同义词 (5-Phenyl-3-ureido)-thiophene-2-carboxamide
    参考
    参考 Baxter, A., et al. 2004. Bioorg. Med. Chem. Lett. 14, 2817.
    产品信息
    CAS号 354810-80-3
    形式 Off-white solid
    Hill配方 C₁₂H₁₁N₃O₂S
    化学配方 C₁₂H₁₁N₃O₂S
    Molar Mass 261.3
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO
    安全信息
    S相 S: 22-24/25-36

    Do not breathe dust.
    Avoid contact with skin and eyes.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,401490,IKK-2 Inhibitor XI - CAS 354810-80-3 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,12-568,Trimethyl-Histone H3 (Lys9) Peptide, biotin conjugate


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