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可用的分析物 品种反应性 主要应用 检测方法 Amylin H ELISA Colorimetric, Fluorescent 描述 产品目录编号 EZHA-52K 描述 Human Amylin ELISA 背景信息 Amylin is a 37 amino acid hormone that is co-secreted with insulin from pancreatic beta cells in response to hyperglycemia. 产品信息 检测方法 ColorimetricFluorescent 精度（%） - Intra-assay: 1.9 ± 0.7
- Inter-assay: 5.2–1.3
应用 应用 This Human Amylin ELISA is used to measure & quantify Amylin levels in Metabolism & Endocrine research. 主要应用 - ELISA
应用说明 50 μl plasma or cell culture supernatant 3.5 hour protocol, room temperature 生物信息 品种反应性 Human 可用的分析物 - Amylin
交叉反应性 This kit will be suitable for the measurement of amylin in rat and feline plasma, however, the precise percent of cross-reactivity is not determined. Entrez基因编号 - NM_000415.1
Entrez基因汇总 Islet, or insulinoma, amyloid polypeptide (IAPP, or amylin) is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta-amyloid (Abeta) assosciated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. 基因符号 - DAP
- IAPP
- AMYLIN
- IAP
- Amylin
UniProt编号 - P10997
UniProt汇总 FUNCTION: SwissProt: P10997 # Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
SIZE: 89 amino acids; 9806 Da
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P10997 # IAPP is the peptide subunit of amyloid found in pancreatic islets of type 2 diabetic patients and in insulinomas.
SIMILARITY: SwissProt: P10997 ## Belongs to the calcitonin family.准确度 - 96 ± 2.5%
理化信息 标准曲线范围 - 1–100 pM
产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 96-well plate
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