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主要应用 CULT 描述 产品目录编号 CC065 Replaces CC066 品牌系列 Chemicon®
商名 - Chemicon
描述 Human Tenascin-C Purified Protein 概述 Purified Human Tenascin-C Protien. Tenascin is known to: 1) play an active role in development of central nervous system and mesenchymal-derived organs; 2) exist in vasculature of tumors in adults; and 3) function in cell adhesion. By SDS-PAGE analysis, the protein migrates around 280-300kD. Alternate Names - Neuronectin
- TN-C
- Tenascin
- Hexabrachion
- Cytotactin
产品信息 演示 Purified protein supplied as a liquid in PBS containing no preservatives. 应用 主要应用 - Cell Culture
应用说明 Cell adhesion assays.
Optimal working dilutions must be determined by end user.生物信息 浓缩 0.1 mg/mL 纯度 > 97% pure by SDS-PAGE 来源 Human glioma cell line (U251). 品种 Human Entrez基因编号 - NM_002160.2
基因符号 - Cytotactin
- TNC
- Hexabrachion
- HXB
- GMEM
- TN
- Neuronectin
- Tenascin-C
- MGC167029
- JI
- TN-C
UniProt编号 - P24821
UniProt汇总 FUNCTION: SwissProt: P24821 # Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
SIZE: 2201 amino acids; 240866 Da
SUBUNIT: Homohexamer; disulfide-linked. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4.
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.
PTM: N-glycosylated (By similarity).
SIMILARITY: SwissProt: P24821 ## Belongs to the tenascin family. & Contains 15 EGF-like domains. & Contains 1 fibrinogen C-terminal domain. & Contains 15 fibronectin type-III domains.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -70ºC for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µg
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