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merck millipore,默克密理博,17-369,Rac2 Activation Assay Kit
产品名称：Rac2 Activation Assay Kit
产品型号：17-369
Non-radioactive Rac2 Activation Assay Kit can be used to precipitate Rac2-GTP from cell lysates & detection by a Rac2 specific monoclonal antibody.
merck millipore,默克密理博,17-369,Rac2 Activation Assay Kit
- 产品介绍
重要规格表
主要应用 ABA 描述 产品目录编号 17-369 品牌系列 Upstate
商名 - Upstate
描述 Rac2 Activation Assay Kit 产品信息 部件 - 100X GDP, 100mM (Cat.# 20-177)
- Rac/cdc42 Assay Reagent (PAK1 PBD, agarose) (Cat.# 14-325)
- Anti-Rac2 (Cat.# 07-604)
- Mg2+ Lysis/Wash Buffer, 5X (Cat.# 20-168)
- 100X GTPγS, 10mM (Cat.# 20-176)
应用 应用 Non-radioactive Rac2 Activation Assay Kit can be used to precipitate Rac2-GTP from cell lysates & detection by a Rac2 specific monoclonal antibody. 主要应用 - Affinity Binding Assay
生物信息 Entrez基因编号 - NM_002872.3
Entrez基因汇总 The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. 基因符号 - HSPC022
- RAC2
- p21-Rac2
- GX
- Gx
- EN-7
UniProt编号 - P15153
UniProt汇总 FUNCTION: SwissProt: P15153 # Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Seems to be involved in the regulation of the NADPH oxidase.
SIZE: 192 amino acids; 21429 Da
SUBUNIT: Interacts with DOCK2, which may activate it.
SUBCELLULAR LOCATION: Cytoplasm. Note=Membrane-associated when activated.
TISSUE SPECIFICITY: Hematopoietic specific.
DISEASE:SwissProt: P15153 # Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome [MIM:608203].
SIMILARITY: SwissProt: P15153 ## Belongs to the small GTPase superfamily. Rho family.产品使用声明 质量保证 Routinely evaluated by Immunoprecipitation of Rac2-GTP from HL-60 cells that had been loaded with GTPγS. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 30 assays 包装 Kit capacity: 30 assays
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