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描述 产品目录编号 AG382 品牌系列 Chemicon®
商名 - Chemicon
描述 Uncoupling Protein 1, control peptide for AB3038 概述 Uncoupling Protein 1 (UCP1) control peptide. Alternate Names - UCP1
产品信息 演示 Liquid in PBS, pH 7.5 with 0.05% sodium azide. 应用 主要应用 - Peptide Inhibition Assay
应用说明 Antibody blocking (AB3038)
Optimal working concentration must be determined by the end user.生物信息 浓缩 1 mg/mL 品种 Rat Entrez基因编号 - NM_021833.3
Entrez基因汇总 Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. 基因符号 - SLC25A7
- UCP1
- Thermogenin
- UCP
UniProt编号 - P25874
UniProt汇总 FUNCTION: SwissProt: P25874 # UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
SIZE: 307 amino acids; 33005 Da
SUBUNIT: Acts as a dimer forming a proton channel.
SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Brown adipose tissue.
SIMILARITY: SwissProt: P25874 ## Belongs to the mitochondrial carrier family. & Contains 3 Solcar repeats.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µg
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