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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB, IHC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT140 描述 Anti-Dynein light chain 2 Antibody Alternate Names - Dynein light chain LC8-type 2
- Dynein light chain 2, cytoplasmic
- 8 kDa dynein light chain b
- DLC8b
背景信息 Eukaryotic cells rely on actin and microtubule-based protein "motors" to generate intracellular movements. These protein "motors" contain specialized domains that hydrolyse ATP to produce force and movement along a cytoskeletal polymer (actin in the case of myosin family and microtubules in the case of the kinesin family and dyneins). Dynein has been implicated in cytoplasmic motile funtions, including chromosomal movement, retrograde organelle and axonal transport, the endocytic pathway, and the organization of the Golgi apparatus. In all cell types, dynein has the same basic structures and is composed of two or three distinct heavy chains (~450 kDa), three intermediate chains (70-125 kDa), and at least four light chains (15-25 kDa). 产品信息 格式 Affinity Purified 控制 - Human heart tissue lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect Dynein light chain 2 using this Anti-Dynein light chain 2 Antibody validated for use in IHC, Western Blotting. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Dynein light chain 2 in human, mouse, and rat heart tissues. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human Dynein light chain 2. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with Human, Mouse, and Rat. Predicted to react with Canine, Bovine, and Porcine based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_542408
基因符号 - DLC2
- DYNLL2
纯化方法 Affinity purified UniProt编号 - Q96FJ2
产品使用声明 质量保证 Evaluated by Western Blot in human heart tissue lysate.
Western Blot Analysis: 5 µg/mL of this antibody detected Dynein light chain 2 in 10 µg of human heart tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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