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  • merck millipore,默克密理博,ABS79,Anti-phospho-mTOR (Ser2159) Antibody

  • merck millipore,默克密理博,ABS79,Anti-phospho-mTOR (Ser2159) Antibody

    产品名称：Anti-phospho-mTOR (Ser2159) Antibody
    产品型号：ABS79
    Anti-phospho-mTOR (Ser2159) Antibody detects level of phospho-mTOR (Ser2159) & has been published & validated for use in Western Blotting, Peptide Inhibition Assay, Dot Blot.

    merck millipore,默克密理博,ABS79,Anti-phospho-mTOR (Ser2159) Antibody

  • 产品介绍
  • merck millipore,默克密理博,ABS79,Anti-phospho-mTOR (Ser2159) Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Zebrafish, H, M, R, ShWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 ABS79
    描述 Anti-phospho-mTOR (Ser2159) Antibody
    Alternate Names
    • Rapamycin target protein 1
    • Serine/threonine-protein kinase mTOR
    • FK506-binding protein 12-rapamycin complex-associated protein 1
    • FKBP12-rapamycin complex-associated protein
    • Mammalian target of rapamycin
    • mTOR
    • Mechanistic target of rapamycin
    • Rapamycin and FKBP12 target 1
    背景信息 The mammalian target of rapamycin (mTOR), also known as FRAP, RAFT, or RAPT, is a ubiquitously expressed serine/threonine kinase that belongs to the phosphoinositide 3-kinase–related kinase (PIKK) family. mTOR functions as a downstream effector in the PI3K pathway and is activated by the Akt kinase. mTOR responds to signals from growth factors and promotes protein synthesis underlying cell proliferation, by activation of the S6 kinase and inhibition of the 4E-BP protein involved in protein translation. Several studies have suggested that the proliferative functions of mTOR may contribute to the development of cancer.
    产品信息
    格式 Affinity Purified
    控制
    • Unmodified and modified mTOR peptides
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-phospho-mTOR (Ser2159) Antibody detects level of phospho-mTOR (Ser2159) & has been published & validated for use in Western Blotting, Peptide Inhibition Assay, Dot Blot.
    主要应用
    • Western Blotting
    应用说明 Western Blot Analysis: A representative lot detected phospho-mTOR (Ser2159) in HEK293 cell lysate. Image courtesy from the laboratory of Dr. Diane Fingar, University of Michigan Medical School.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to human mTOR phosphorylated at Ser2159.
    表位 Phosphorylated at Ser2159
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 This antibody recognizes mTOR phosphorylated at Ser2159.
    品种反应性 ZebrafishHumanMouseRatSheep
    Species Reactivity Note Demonstrated to react with Human. Predicted to react with Mouse, Rat, Zebra Fish, and Sheep based on 100% sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_004949
    基因符号
    • RAPT1
    • MTOR
    • FRAP
    • FRAP1
    • FRAP2
    • RAFT1
    纯化方法 Affinity purified
    UniProt编号
    • P42345
    产品使用声明
    质量保证 Evaluated by Dot Blot in unmodified and modified mTOR peptides.

    Dot Blot Specificity Analysis: Unmodified and modified mTOR peptides (see Table) were probed with Anti-phospho-mTOR (Ser2159) (1:1,000 dilution).
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,ABS79,Anti-phospho-mTOR (Ser2159) Antibody

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