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品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Purified Polyclonal Antibody 描述 产品目录编号 ABS621 Replaces MABS404 描述 Anti-NAT1 Antibody Alternate Names - NAT1
- Arylamine N-acetyltransferase 1
- Arylamide acetylase 1
- Monomorphic arylamine N-acetyltransferase
- MNAT
- N-acetyltransferase type 1
- NAT-1
背景信息 The protein named Arylamine N-acetyltransferase 1 or alternatively Arylamide acetylase 1, Monomorphic arylamine N-acetyltransferase (MNAT), or N-acetyltransferase type 1 (NAT-1) and encoded by the human gene named NAT1 or AAC1 is a detoxifying enzyme that helps to metabolize drugs and other xenobiotics. NAT1 also functions in folate catabolism. Interestingly, NAT1 is one of two N-acetyltransferase isozymes in humans that also catalyze both N-acetylation (usually deactivation) and O-acetylation (usually activation) of aromatic and heterocyclic amine carcinogens. Epidemiological studies suggest that the NAT1 and NAT2 acetylation polymorphisms modify risk of developing urinary bladder, colorectal, breast, head and neck, lung, and possibly prostate cancers. NAT1 is expressed principally in the liver but can also be found expressed in kidney, lung and trachea, with minor expression seen in most other tissues as well. We offer a rabbit polyclonal Anti-NAT1 Antibody that has been validated in western blot on PC3 cell extracts and in paraffin embedded immunohistochemistry on human breast cancer tissue sections and in fluorescent immunocytochemistry on HeLa cells in culture. 产品信息 格式 Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Anti-NAT1 Antibody is a highly specific rabbit polyclonal antibody, that targets NAT1 & has been tested in western blotting, IHC & Immunofluorescence. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected NAT1 in human breast cancer tissue.
Immunofluorescence Analysis: A 1:25 dilution from a representative lot detected NAT1 in HeLa cells.生物信息 免疫原品种 Histidine-tagged fusion protein corresponding to human NAT1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - AAC1
- NAT1
纯化方法 Antigen Affinity purified UniProt编号 - P18440
产品使用声明 质量保证 Evaluated by Western Blotting in PC-3 cell lysate.
Western Blotting Analysis: A 1:1,200 dilution of this antibody detected NAT1 in PC-3 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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