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品种反应性 主要应用 宿主 格式 抗体类型 M, H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS480 描述 Anti-RGN Antibody Alternate Names - RGN
- SMP-30
- Senescence marker protein 30
- GNL
- Gluconolactonase
- RC
- Regucalcin
背景信息 The protein called Regucalcin (RC) or gluconolactonase (GNL), or Senescence marker protein 30 (SMP-30) and encoded by the human gene RGN/SMP30 is calcium binding protein that is involved in the synthesis of vitamin C in non primates. In primates RGN is mostly involved in modulating calcium signaling and calcium dependent cellular processes and enzyme activities in many cell types. RGN also functions enzymatically as a lactonase, and RGN hydrolyzes various carbohydrate lactones. RGN is also implicated as an organophosphate hydrolase, with the ability to hydrolyze diisopropyl phosphofluoridate and other nerve agents. RGN was originally identified as an aging marker as well as a marker of cold stress. RGN is expressed in many cells but is particularly high in liver and kidney cytoplasm. EMD-Millipore’s Anti-RGN rabbit polyclonal antibody has been tested in on mouse liver extracts and in paraffin embedded immunohistochemistry on human kidney tissue sections. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Anti-RGN Antibody is a highly specific rabbit polyclonal antibody, that targets Regucalcin & has been tested in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected RGN in human kidney tissue.
生物信息 免疫原品种 GST-tagged fusion protein corresponding to human RGN. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 MouseHuman Species Reactivity Note Human, Mouse 抗体类型 Polyclonal Antibody 基因符号 - SMP30
- RGN
纯化方法 Antigen Affinity purified UniProt编号 - Q15493
产品使用声明 质量保证 Evaluated by Western Blotting in mouse liver tissue lysate.
Western Blotting Analysis: A 1:600 dilution of this antibody detected RGN in mouse liver tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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