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品种反应性 主要应用 宿主 格式 抗体类型 M, H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS449 描述 Anti-UNG1 Antibody Alternate Names - UDG1
- Uracil-DNA glycosylase 1
背景信息 Uracil-DNA glycosylase 1 (UNG1), also known as UDG1, DGU or UNG15, hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, and as a result it releases free uracil. UNG1 excises uracil residues from the DNA. This event could be a result of faulty incorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Uniport describes two isoforms. The fist isoform is widely expressed with the highest expression in skeletal muscle, heart and testicles. The second isoform has the highest expression levels in tissues containing proliferating cells. Recent studies have shown that defects in UNG are a cause of immunodeficiency with hyper-IgM type 5 (HIGM5). HIGM5 is a rare immunodeficiency syndrome characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE, resulting in a profound susceptibility to bacterial infections. 产品信息 格式 Affinity Purified 控制 - C2C12 cell lysate
演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-UNG1 Antibody is a highly specific rabbit polyclonal antibody, that targets Uracil-DNA glycosylase 1 & has been tested in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 2 µg/mL from a representative lot detected UNG1 in human heart tissue.
Immunofluorescence Analysis: 20 µg/mL from a representative lot detected UNG1 in human heart tissue.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the C-terminus of human UNG1. 表位 C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes the C-terminus of UNG1. 品种反应性 MouseHuman 抗体类型 Polyclonal Antibody 基因符号 - UNG15
- UNG
- DGU
- UNG1
纯化方法 Antigen Affinity purified UniProt编号 - P13051
产品使用声明 质量保证 Evaluated by Western Blotting in C2C12 cell lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected UNG1 in 15 µg of C2C12 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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