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merck millipore,默克密理博,ABS218,Anti-phospho-DBC1 (Thr454) Antibody
产品名称：Anti-phospho-DBC1 (Thr454) Antibody
产品型号：ABS218
Anti-phospho-DBC1 (Thr454) Antibody is an antibody against phospho-DBC1 (Thr454) for use in Western Blotting, Peptide Inhibition Assay.
merck millipore,默克密理博,ABS218,Anti-phospho-DBC1 (Thr454) Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS218 描述 Anti-phospho-DBC1 (Thr454) Antibody Alternate Names - Deleted in breast cancer gene 1 protein
- DBC-1
- DBC.1
- p30 DBC
- DBIRD complex subunit KIAA1967
背景信息 Deleted in breast cancer gene 1 protein (DBC1) is a large, nuclear protein with multiple functions in cell survival that binds directly to the estrogen receptor α (ERα) hormone-binding domain in a strict ligand-independent manner. DBC1 promotes p53-mediated apoptosis by binding to and inhibiting the deacetylase activity of SirT1, resulting in increased p53 acetylation levels and activity. It is ubiquitously expressed in 84 to 100% of neoplastic breast, lung, and colon tissues. 产品信息 格式 Affinity Purified 控制 - Untreated and etoposide treated Jurkat cell lysates
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-phospho-DBC1 (Thr454) Antibody is an antibody against phospho-DBC1 (Thr454) for use in Western Blotting, Peptide Inhibition Assay. 主要应用 - Western Blotting
应用说明 Peptide Inhibition Assay: A 1:500 dilution from a representative lot blocked DBC-1 phosphorylated at Thr454 in untreated and etoposide treated Jurkat cell lysates. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human DBC-1 phosphorylated at Thr454. 表位 Phosphorylated Thr454 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes DBC1 phosphorylated at Thr454. 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_066997
基因符号 - DBC1
- KIAA1967
纯化方法 Affinity purified UniProt编号 - Q8N163
产品使用声明 质量保证 Evaluated by Western Blot in untreated and etoposide treated Jurkat cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected DBC-1 phosphorylated at Thr454 in 10 µg of etoposide treated Jurkat cell lysates.
使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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