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merck millipore,默克密理博,ABN458,Anti-Choline Transporter Antibody
产品名称:Anti-Choline Transporter Antibody
产品型号:ABN458
Anti-Choline Transporter Antibody is a highly specific rabbit polyclonal antibody, that targets Choline Transporter & has been tested in western blotting & IHC (Paraffin).
merck millipore,默克密理博,ABN458,Anti-Choline Transporter Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN458 Replaces AB5960;AB5966 描述 Anti-Choline Transporter Antibody Alternate Names - Solute carrier family 5 member 7
- High affinity choline transporter 1
- Hemicholinium-3-sensitive choline transporter
- CHT
背景信息 The protein named Choline Transporter or Hemicholinium-3-sensitive choline transporter (CHT), and encoded by the gene SLC5A7/CHT1, is the high affinity choline transporter in neurons. Choline is the rate limiting step in acetylcholine synthesis an important neurotransmitter. Acetylcholine is a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. The choline transporter is localized to the cell membrane and is expressed in cholinergic neurons particularly in the putamen, spinal cord and medulla. Defects in the choline transporter may be associated with a syndrome named distal spinal muscular atrophy with vocal cord paralysis. The choline transporter protein is a Na+ and Cl- dependent transporter that can be inhibited by nanomolar concentrations of the chemical compound hemicholinium 3, a compound often used to deplete acetylcholine stores. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-Choline Transporter Antibody is a highly specific rabbit polyclonal antibody, that targets Choline Transporter & has been tested in western blotting & IHC (Paraffin). 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Choline Transporter in rat spinal cord and human cerebral cortex tissue. 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to the C-terminus of human Choline Transporter. 表位 C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_068587
基因符号 - CHT1
- SLC5A7
纯化方法 Affinity purified UniProt编号 - Q9GZV3
产品使用声明 质量保证 Evaluated by Western Blotting in rat spinal cord tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected Choline Transporter in 10 µg of rat spinal cord tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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