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merck millipore,默克密理博,ABN414,Anti-LRRC4 Antibody
产品名称：Anti-LRRC4 Antibody
产品型号：ABN414
Anti-LRRC4 Antibody is a highly specific rabbit polyclonal antibody, that targets Leucine-rich repeat-containing protein 4 & has been tested in western blotting & IHC.
merck millipore,默克密理博,ABN414,Anti-LRRC4 Antibody
- 产品介绍
- merck millipore,默克密理博,ABN414,Anti-LRRC4 Antibody
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN414 描述 Anti-LRRC4 Antibody Alternate Names - NGL-2
- Leucine-rich repeat-containing protein 4
- Brain tumor-associated protein BAG
- Nasopharyngeal carcinoma-associated gene 14 protein
- Netrin-G2 ligand
背景信息 Leucine-rich repeat-containing protein 4, or LRRC4, also known as Nasopharyngeal carcinoma-associated gene 14 protein or Netrin-G2 ligand (NGL-2), and encoded by the gene LRRC4/BAG, is a synaptic adhesion protein that regulates the formation of excitatory synapses through the recruitment of key pre and post synaptic proteins. LRRC4 is particularly important in auditory synaptic responses and LRRC4 is a key regulator of input-specific synapse development in the hippocampus as well. Finally, LRRC4 appears important in the suppression of glioma cancers in the brain and is specifically down regulated in tumors, and is currently being investigated as a potential anti-cancer target. LRRC4 is localized to the cell junctions and synapses. It is a cell membrane bound, post-synaptic, protein, and LRRC4’s expression is brain specific. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-LRRC4 Antibody is a highly specific rabbit polyclonal antibody, that targets Leucine-rich repeat-containing protein 4 & has been tested in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Lrrc4 in rat hippocampus tissue, whereas a 1:500 dilution from a representative lot detected LRRC4 in human cerebellum and thalamus tissues. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the extracellular domain of human LRRC4. 表位 Extracellular domain 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with Human, Mouse, and Rat. Predicted to react with Bovine, Canine, and Feline based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 -
">NP_071426
基因符号 - NAG14
- LRRC4
- BAG
纯化方法 Affinity purified UniProt编号 - Q9HBW1
产品使用声明 质量保证 Evaluated by Western Blotting in human brain tissue lysate.
Western Blotting: 1 µg/mL of this antibody detected LRRC4 in 10 µg of human brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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