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品种反应性 主要应用 宿主 格式 抗体类型 M, H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABF222 描述 Anti-UHRF1BP1 Antibody Alternate Names - UHRF1 binding protein 1
- Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1
- ICBP90-binding protein 1
背景信息 UHRF1-binding protein 1 (UHRF1BP1), also known as ICBP90-binding protein 1 and Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1, is a transcription and cell cycle regulator. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells and may act as a negative regulator of cell growth. UHRF1BP1 is implied to be an important target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells. Additionally, UHRF1BP1 binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger and an SRA (SET- and RING-associated) domain. The PHD finger defines the binding specificity and an SRA domain promotes binding activity. 产品信息 格式 Affinity Purified 控制 - Mouse kidney tissue lysate
演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-UHRF1BP1 Antibody is a highly specific rabbit polyclonal antibody, that targets UHRF1-binding protein 1 & has been tested in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected UHRF1BP1 in human kidney tissue. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human UHRF1BP1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 MouseHuman 抗体类型 Polyclonal Antibody 基因符号 - UHRF1BP1
纯化方法 Antigen Affinity purified UniProt编号 - Q6BDS2
产品使用声明 质量保证 Evaluated by Western Blotting in mouse kidney tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected UHRF1BP1 in 15 µg of mouse kidney tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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