merck millipore,默克密理博,AB9519,Anti-P2Y4 Antibody, Pyrimidinergic Receptor

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	IH(P)	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	AB9519
品牌系列	Chemicon®
商名	Chemicon
描述	Anti-P2Y4 Antibody, Pyrimidinergic Receptor

产品信息
格式	Affinity Purified
演示	Affinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.

应用
应用	This Anti-P2Y4 Antibody, Pyrimidinergic Receptor is validated for use in IH(P) for the detection of P2Y4.
主要应用	Immunohistochemistry (Paraffin)
应用说明	Immunohistochemistry on paraffin embedded tissue sections. Optimal working dilutions must be determined by the end user.

生物信息
免疫原品种	Synthetic peptide from the 1st cytoplasmic domain of human P2Y4.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
特异性	Recognizes P2Y4, Pyrimidinergic Receptor.
品种反应性	Human
抗体类型	Polyclonal Antibody
Entrez基因编号	NM_002565.3
Entrez基因汇总	The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP.
基因符号	P2Y4 P2RY4 UNR NRU P2P
UniProt编号	P51582
UniProt汇总	FUNCTION: SwissProt: P51582 # Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP. SIZE: 365 amino acids; 40963 Da SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Pancreas. PTM: Phosphorylation of Ser-333 and Ser-334 is a key step in agonist-dependent desensitization and loss of surface P2RY4. This phosphorylation does not involve PKC, nor other calcium activated kinases. SIMILARITY: SwissProt: P51582 ## Belongs to the G-protein coupled receptor 1 family.

产品使用声明
销售限制	This product is not available for sale in Japan.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

包装信息
数量	50 µg

merck millipore,默克密理博,AB9519,Anti-P2Y4 Antibody, Pyrimidinergic Receptor

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