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品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABF220 描述 Anti-RP105 Antibody Alternate Names - Radioprotective 105 kDa protein
- Lymphocyte antigen 64
- CD180 antigen precursor
- CD180 antigen
背景信息 Radioprotective 105 kDa protein (RP105), also known as Lymphocyte antigen 64 (LY64) or CD180 antigen precursor (CD180 antigen, CD180), is a member of the Toll-like receptor (TLRs) family. It contains 19 LRR (leucine-rich) repeats, 1 LRRCT and 1 LRRNT domains. Recent studies suggest that RP105 may interact with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Additionally, it is implied that RP105 is involved in NF-kappa-B activation, as well as the life/death decision of B-cells. It has also been suggested that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes. RP105 is expressed mainly on mature peripherical B cells, and is detected in spleen, lymph node, and appendix. 产品信息 格式 Affinity Purified 控制 - Human spleen tissue lysate
演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-RP105 Antibody is a highly specific rabbit polyclonal antibody, that targets Radioprotective 105 kDa protein & has been tested in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 2 µg/mL from a representative lot detected RP105 in human spleen tissue. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human RP105. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - RP105
- CD180
- LY64
纯化方法 Antigen Affinity purified UniProt编号 - Q99467
产品使用声明 质量保证 Evaluated by Western Blotting in human spleen tissue lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected RP105 in 15 µg of human spleen tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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