merck millipore,默克密理博,ABF203,Anti-S1P1 Antibody

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
M	IHC, WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABF203
描述	Anti-S1P1 Antibody
Alternate Names	CD363 Sphingosine-1-phosphate receptor 1 S1PR1 EDG1 ECGF1 S1P1 Endothelial differentiation G-protein coupled receptor 1 Sphingosine 1-phosphate receptor Edg-1 S1P receptor Edg-1
背景信息	Sphingosine-1-phosphate receptor 1 (S1PR1, S1P1), also known as Endothelial differentiation G-protein coupled receptor 1 (EDG1, ECGF1), Sphingosine 1-phosphate receptor Edg-1, S1P receptor Edg-1, is a bioactive lysophospholipid that evokes diverse physiological effect on most types of cells and tissues. Recent studies suggest that S1P1 promotes lymph node egression by overcoming retention signals mediated by CCR7 and G alpha i-protein-coupled receptor signaling. S1P1 may be involved in the processes that regulate the differentiation of endothelial cells. S1P1 is expressed highly in endothelial cells, and to a lesser extent in vascular smooth muscle cells, fibroblasts, melanocytes and cells of epithelioid origin.

产品信息
格式	Affinity Purified
控制	Mouse thymus tissue lysate
演示	Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

应用
应用	Detect S1P1 using this rabbit polyclonal antibody, Anti-S1P1 Antibody validated for use in western blotting & IHC.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected S1P1 in mouse thymus tissue.

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to human S1P1.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
品种反应性	Mouse
Species Reactivity Note	Demonstrated to react with Mouse. Predicted to react with Human based on immunogen design.
抗体类型	Polyclonal Antibody
基因符号	S1PR1
纯化方法	Antigen Affinity purified
UniProt编号	P21453

产品使用声明
质量保证	Evaluated by Western Blotting in mouse thymus tissue lysate. Western Blotting Analysis: 2 µg/mL of this antibody detected S1P1 in 15 µg of mouse thymus tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,ABF203,Anti-S1P1 Antibody

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