merck millipore,默克密理博,ABE543,Anti-PRDM16 Antibody

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	IHC, WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABE543
描述	Anti-PRDM16 Antibody
Alternate Names	MDS1/EVI1-like gene 1 PR domain zinc finger protein 16 PR domain-containing protein 16 Transcription factor MEL1
背景信息	PR domain zinc finger protein 16 (PRDM16) is also called Transcription factor MEL1 (MDS1/EVI1-like gene 1). PRDM16 is a zinc finger transcription factor and contains an N-terminal PR domain. PRDM16 is expressed in the uterus and kidney. PRDM16 regulates transcription through DNA binding and plays a role in the differentiation of myoblastic precursors into brown adipose tissue (BAT), and represses TGF-beta signalling. Translocations in PRDM16 occur in subsets of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) cases.

产品信息
格式	Affinity Purified
演示	Purified rabbit serum in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	Detect PRDM16 using this rabbit polyclonal antibody, Anti-PRDM16 Antibody validated for use in western blotting, IP & IHC.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunoprecipitation Analysis: 10 µg from a representative lot immunoprecipitated PRDM16 from 500 µg of K562 nuclear extract. Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected PRDM16 in human kidney tissues.

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to human PRDM16.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
品种反应性	Human
Species Reactivity Note	Demonstrated to react with Human. Predicted to react with Non-Human Primate, Horse, Bovine, Canine, and Guinea Pig based on 100% sequence homology.
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_071397
基因符号	PFM13 PRDM16 MEL1
纯化方法	Affinity purified
UniProt编号	Q9HAZ2

产品使用声明
质量保证	Evaluated by Western Blotting in LNCaP nuclear extract. Western Blotting Analysis: 2 µg/mL of this antibody detected PRDM16 in 10 µg of LNCaP nuclear extract.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,ABE543,Anti-PRDM16 Antibody

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